© Copyright 2026 American Medical Association. All rights reserved.
The CPT® Code 84155 refers to a laboratory test that measures the total protein levels in a sample of serum, plasma, or whole blood, excluding methods that utilize refractometry. This test is essential for assessing the overall protein content in the blood, which is crucial for various physiological functions. Total protein levels are typically reported alongside the albumin to globulin (A/G) ratio, providing insight into the balance between these two major protein types. In a healthy individual, albumin levels are generally slightly higher than globulin levels. The total protein test is instrumental in monitoring a patient's nutritional status and can aid in the diagnosis of several medical conditions, particularly those affecting the kidneys and liver. Elevated total protein levels may suggest the presence of chronic inflammation, viral infections such as hepatitis, HIV, or conditions like multiple myeloma. Conversely, decreased protein levels can indicate issues such as malnutrition or malabsorption syndromes, including celiac disease or inflammatory bowel disease. The test requires a blood sample, which is obtained through a venipuncture procedure that is reported separately. The analysis of the blood sample is performed using quantitative spectrophotometry, a method that quantifies the concentration of proteins in the sample.
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