CPT® Code 85045

An automated reticulocyte count is a laboratory procedure that quantifies the number of reticulocytes, which are immature red blood cells (RBCs) that are newly released from the bone marrow into the bloodstream. These reticulocytes typically circulate in the peripheral blood for a duration of 1 to 2 days before they mature into fully developed red blood cells. The primary purpose of performing a reticulocyte count is to assess the bone marrow's response to the body's demand for red blood cells, particularly in situations where there is a noted decrease in the overall red blood cell count, hemoglobin levels, or hematocrit measurements. This test is particularly useful in diagnosing and monitoring various medical conditions that affect red blood cell production and survival. Indications for conducting a reticulocyte count include conditions such as vitamin B12 or folate deficiency, which can impair red blood cell production; kidney disease, where erythropoietin production may be affected; and during or after chemotherapy or bone marrow transplant, where the bone marrow's ability to produce blood cells may be compromised. Additionally, patients receiving treatment with erythropoietin or darbepoetin, medications that stimulate red blood cell production, may also require monitoring of reticulocyte levels to evaluate the effectiveness of the treatment. The automated reticulocyte count is performed using specialized blood cell counting instruments, which provide a precise measurement of reticulocyte levels in the blood sample obtained from the patient. This procedure is reported with the CPT® code 85045 when performed independently, while additional cellular parameters can be measured using other specific codes.