Coding Ahead
CasePilot
Medical Coding Assistant
Case2Code
Search and Code Lookup Tool
CareerCenter
Medical Coding Job Board
Log in Register free account

Need help choosing the right code?

Ask CasePilot about procedures, modifiers, bundling, and coding guidance.

Try CasePilot

Official Description

Allergen specific IgE; quantitative or semiquantitative, crude allergen extract, each

© Copyright 2026 American Medical Association. All rights reserved.

Common Language Description

The CPT® Code 86003 refers to a laboratory test that measures allergen-specific immunoglobulin E (IgE) levels in the blood, utilizing either quantitative or semiquantitative methods. This test is commonly known as the radioallergosorbent test (RAST) and is classified as an in vitro allergy test, distinguishing it from skin tests, which are considered in vivo tests. The primary purpose of this test is to identify various IgE antibodies that are linked to allergic reactions and symptoms. These reactions can be triggered by a wide range of allergens, including food items, animal dander, dust mites, molds, grasses, trees, weeds, and insect stings or bites. The quantitative or semiquantitative nature of the test means that it provides results in IgE units, which can be interpreted using a standardized scoring system to assess the severity of the allergy. Advances in allergy testing technology have enhanced the ability to detect allergen proteins, even those present in minimal quantities, thereby improving the identification of specific allergies. Typically, multiple allergens are tested simultaneously in an allergy panel or profile, which may include a variety of respiratory, food, or environmental allergens that are relevant to a specific geographic area or demographic group, such as adults or children. These panels can encompass a dozen or more common allergens and may be categorized into specific profiles, such as upper respiratory allergy profiles, adult food allergy profiles, child food allergy profiles, or child environmental allergy profiles. For each crude allergen extract tested using a quantitative or semiquantitative technique, the CPT® Code 86003 is reported. It is important to note that this code is distinct from CPT® Code 86005, which is used for qualitative multiallergen screening tests that only determine the presence or absence of specific IgE without providing quantitative measurements or allergy scores.

© Copyright 2026 Coding Ahead. All rights reserved.

1. Indications

The CPT® Code 86003 is indicated for use in various clinical scenarios where the identification of specific IgE antibodies is necessary to diagnose allergies. The following conditions and symptoms may warrant the performance of this test:

  • Allergic Rhinitis - Patients experiencing symptoms such as sneezing, nasal congestion, and itchy eyes may be tested to identify specific allergens triggering their symptoms.
  • Food Allergies - Individuals with suspected food allergies, presenting with symptoms like hives, gastrointestinal distress, or anaphylaxis, may undergo this test to determine specific food allergens.
  • Asthma - Patients with asthma may be tested to identify environmental or food allergens that could exacerbate their condition.
  • Atopic Dermatitis - Individuals with eczema or atopic dermatitis may be tested to identify potential allergens contributing to their skin condition.
  • Insect Allergies - Patients with a history of allergic reactions to insect stings or bites may be tested to identify specific insect allergens.

2. Procedure

The procedure for performing the test associated with CPT® Code 86003 involves several key steps, which are outlined below:

  • Step 1: Sample Collection - A blood sample is collected from the patient, typically via venipuncture. This sample serves as the basis for the allergen-specific IgE testing.
  • Step 2: Preparation of Crude Allergen Extracts - Crude allergen extracts are prepared from various sources, such as plants, animals, or environmental materials. These extracts contain the proteins that may trigger allergic responses.
  • Step 3: Testing Methodology - The blood sample is subjected to a quantitative or semiquantitative testing method, which may involve techniques such as enzyme-linked immunosorbent assay (ELISA) or other immunoassays. The test measures the concentration of specific IgE antibodies in response to the crude allergen extracts.
  • Step 4: Interpretation of Results - The results are interpreted based on the levels of IgE detected. Quantitative results provide specific IgE units, which can be compared against established reference ranges to assess the likelihood of an allergy.
  • Step 5: Reporting - The findings are compiled into a report that details the specific allergens tested and the corresponding IgE levels, which can then be used by healthcare providers to guide diagnosis and treatment.

3. Post-Procedure

After the completion of the allergen-specific IgE testing, patients may not require any specific post-procedure care, as the blood draw is a routine procedure. However, it is essential for healthcare providers to discuss the results with the patient, explaining the implications of the IgE levels and how they relate to the patient's symptoms. Based on the findings, further management strategies may be recommended, which could include avoidance of identified allergens, additional testing, or treatment options such as allergy medications or immunotherapy. Patients should also be advised to monitor their symptoms and report any significant changes to their healthcare provider.

Short Descr ALLG SPEC IGE CRUDE XTRC EA
Medium Descr ALLERGEN SPEC IGE CRUDE ALLERGEN EXTRACT EACH
Long Descr Allergen specific IgE; quantitative or semiquantitative, crude allergen extract, each
Status Code Statutory Exclusion (from MPFS, may be paid under other methodologies)
Global Days XXX - Global Concept Does Not Apply
PC/TC Indicator (26, TC) 9 - Not Applicable
Multiple Procedures (51) 9 - Concept does not apply.
Bilateral Surgery (50) 9 - Concept does not apply.
Physician Supervisions 09 - Concept does not apply.
Assistant Surgeon (80, 82) 9 - Concept does not apply.
Co-Surgeons (62) 9 - Concept does not apply.
Team Surgery (66) 9 - Concept does not apply.
Diagnostic Imaging Family 99 - Concept Does Not Apply
CLIA Waived (QW) No
APC Status Indicator Conditionally packaged laboratory tests
Type of Service (TOS) 5 - Diagnostic Laboratory
Berenson-Eggers TOS (BETOS) T1H - Lab tests - other (non-Medicare fee schedule)
MUE 70
CCS Clinical Classification 235 - Other Laboratory
91 Repeat clinical diagnostic laboratory test: in the course of treatment of the patient, it may be necessary to repeat the same laboratory test on the same day to obtain subsequent (multiple) test results. under these circumstances, the laboratory test performed can be identified by its usual procedure number and the addition of modifier 91. note: this modifier may not be used when tests are rerun to confirm initial results; due to testing problems with specimens or equipment; or for any other reason when a normal, one-time, reportable result is all that is required. this modifier may not be used when other code(s) describe a series of test results (eg, glucose tolerance tests, evocative/suppression testing). this modifier may only be used for laboratory test(s) performed more than once on the same day on the same patient.
90 Reference (outside) laboratory: when laboratory procedures are performed by a party other than the treating or reporting physician or other qualified health care professional, the procedure may be identified by adding modifier 90 to the usual procedure number.
GA Waiver of liability statement issued as required by payer policy, individual case
GZ Item or service expected to be denied as not reasonable and necessary
59 Distinct procedural service: under certain circumstances, it may be necessary to indicate that a procedure or service was distinct or independent from other non-e/m services performed on the same day. modifier 59 is used to identify procedures/services, other than e/m services, that are not normally reported together, but are appropriate under the circumstances. documentation must support a different session, different procedure or surgery, different site or organ system, separate incision/excision, separate lesion, or separate injury (or area of injury in extensive injuries) not ordinarily encountered or performed on the same day by the same individual. however, when another already established modifier is appropriate it should be used rather than modifier 59. only if no more descriptive modifier is available, and the use of modifier 59 best explains the circumstances, should modifier 59 be used. note: modifier 59 should not be appended to an e/m service. to report a separate and distinct e/m service with a non-e/m service performed on the same date, see modifier 25.
XU Unusual non-overlapping service, the use of a service that is distinct because it does not overlap usual components of the main service
77 Repeat procedure by another physician or other qualified health care professional: it may be necessary to indicate that a basic procedure or service was repeated by another physician or other qualified health care professional subsequent to the original procedure or service. this circumstance may be reported by adding modifier 77 to the repeated procedure or service. note: this modifier should not be appended to an e/m service.
GY Item or service statutorily excluded, does not meet the definition of any medicare benefit or, for non-medicare insurers, is not a contract benefit
76 Repeat procedure or service by same physician or other qualified health care professional: it may be necessary to indicate that a procedure or service was repeated by the same physician or other qualified health care professional subsequent to the original procedure or service. this circumstance may be reported by adding modifier 76 to the repeated procedure or service. note: this modifier should not be appended to an e/m service.
GW Service not related to the hospice patient's terminal condition
Q4 Service for ordering/referring physician qualifies as a service exemption
GV Attending physician not employed or paid under arrangement by the patient's hospice provider
26 Professional component: certain procedures are a combination of a physician or other qualified health care professional component and a technical component. when the physician or other qualified health care professional component is reported separately, the service may be identified by adding modifier 26 to the usual procedure number.
XS Separate structure, a service that is distinct because it was performed on a separate organ/structure
CC Procedure code change (use 'cc' when the procedure code submitted was changed either for administrative reasons or because an incorrect code was filed)
GX Notice of liability issued, voluntary under payer policy
Date
Action
Notes
2018-01-01 Changed Medium and short descriptions changed.
1994-01-01 Added First appearance in code book in 1994.
Code
Description
Code
Description
CasePilot

Get instant expert-level medical coding assistance.

Ask about:
CPT Codes Guidelines Modifiers Crosswalks NCCI Edits Compliance Medicare Coverage
Example: "What is CPT code 99213?" or "Guidelines for E/M services"