CPT® Code 86005

The CPT® Code 86005 refers to a specific laboratory test known as the allergen specific IgE qualitative multiallergen screen. This test is commonly recognized as a radioallergosorbent test (RAST) and is categorized as an in vitro test, meaning it is conducted using a blood sample rather than through skin testing (in vivo). Unlike many allergy tests that yield quantitative or semiquantitative results—providing IgE units that can be interpreted with a scoring system—this particular test focuses solely on the qualitative aspect. It determines the presence or absence of specific IgE antibodies associated with various allergic reactions. The allergens tested can include a wide range of substances such as foods, animal dander, dust mites, molds, grasses, trees, weeds, and insects. Recent advancements in allergy testing technology have enhanced the ability to detect allergen proteins, even those present in minimal quantities, thereby improving the identification of specific allergies. Typically, the test is performed as part of an allergy panel or profile, which may assess multiple allergens relevant to a particular geographic area or demographic group, such as adults or children. These panels can encompass a variety of common allergens, including those associated with upper respiratory allergies or specific food allergies in children. It is important to note that while the qualitative multiallergen screen (CPT® Code 86005) identifies whether specific IgE is present, it does not provide quantitative measurements or an allergy score, which distinguishes it from other testing codes such as CPT® Code 86003, which is used for quantitative or semiquantitative testing of crude allergen extracts.