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Official Description

Allergen specific IgE; qualitative, multiallergen screen (eg, disk, sponge, card)

© Copyright 2026 American Medical Association. All rights reserved.

Common Language Description

The CPT® Code 86005 refers to a specific laboratory test known as the allergen specific IgE qualitative multiallergen screen. This test is commonly recognized as a radioallergosorbent test (RAST) and is categorized as an in vitro test, meaning it is conducted using a blood sample rather than through skin testing (in vivo). Unlike many allergy tests that yield quantitative or semiquantitative results—providing IgE units that can be interpreted with a scoring system—this particular test focuses solely on the qualitative aspect. It determines the presence or absence of specific IgE antibodies associated with various allergic reactions. The allergens tested can include a wide range of substances such as foods, animal dander, dust mites, molds, grasses, trees, weeds, and insects. Recent advancements in allergy testing technology have enhanced the ability to detect allergen proteins, even those present in minimal quantities, thereby improving the identification of specific allergies. Typically, the test is performed as part of an allergy panel or profile, which may assess multiple allergens relevant to a particular geographic area or demographic group, such as adults or children. These panels can encompass a variety of common allergens, including those associated with upper respiratory allergies or specific food allergies in children. It is important to note that while the qualitative multiallergen screen (CPT® Code 86005) identifies whether specific IgE is present, it does not provide quantitative measurements or an allergy score, which distinguishes it from other testing codes such as CPT® Code 86003, which is used for quantitative or semiquantitative testing of crude allergen extracts.

© Copyright 2026 Coding Ahead. All rights reserved.

1. Indications

The allergen specific IgE qualitative multiallergen screen (CPT® Code 86005) is indicated for the evaluation of patients who exhibit symptoms suggestive of allergic reactions. This test is particularly useful in identifying specific IgE antibodies associated with various allergens, which may include:

  • Food Allergies - Symptoms may include gastrointestinal distress, skin reactions, or respiratory issues following the ingestion of certain foods.
  • Environmental Allergies - Symptoms such as sneezing, nasal congestion, or itchy eyes may arise from exposure to allergens like pollen, dust mites, or mold.
  • Animal Dander Allergies - Reactions may occur in individuals exposed to pets or other animals, leading to respiratory symptoms or skin irritations.
  • Insect Allergies - Reactions to insect stings or bites can cause significant allergic responses, which may be evaluated through this test.

2. Procedure

The procedure for conducting the allergen specific IgE qualitative multiallergen screen involves several key steps:

  • Sample Collection - A blood sample is collected from the patient, which serves as the basis for the allergen testing. This is typically done through venipuncture, where a needle is inserted into a vein to draw blood.
  • Preparation of the Test Medium - The collected blood sample is processed to isolate serum, which contains the IgE antibodies. This serum is then prepared for testing using a disc, sponge, or card that contains various allergens.
  • Application of Allergens - The prepared serum is applied to the testing medium that has been pre-coated with specific allergens. This allows for the interaction between the IgE antibodies in the serum and the allergens present on the medium.
  • Incubation - The testing medium is incubated for a specified period, allowing sufficient time for any allergen-specific IgE antibodies to bind to the allergens on the medium.
  • Detection - After incubation, the test is evaluated to determine the presence or absence of specific IgE antibodies. This qualitative assessment indicates whether the patient has an allergy to the tested substances.

3. Post-Procedure

Post-procedure care for the allergen specific IgE qualitative multiallergen screen is generally minimal, as the test is non-invasive and involves only a blood draw. Patients may be advised to maintain hydration and can typically resume normal activities immediately following the test. Results are usually interpreted by a healthcare provider, who will discuss the findings with the patient and may recommend further testing or treatment based on the results. It is important for patients to follow up with their healthcare provider to understand the implications of the test results and to develop an appropriate management plan for any identified allergies.

Short Descr ALLG SPEC IGE MULTIALLG SCR
Medium Descr ALLERGEN SPEC IGE QUAL MULTIALLERGEN SCREEN
Long Descr Allergen specific IgE; qualitative, multiallergen screen (eg, disk, sponge, card)
Status Code Statutory Exclusion (from MPFS, may be paid under other methodologies)
Global Days XXX - Global Concept Does Not Apply
PC/TC Indicator (26, TC) 9 - Not Applicable
Multiple Procedures (51) 9 - Concept does not apply.
Bilateral Surgery (50) 9 - Concept does not apply.
Physician Supervisions 09 - Concept does not apply.
Assistant Surgeon (80, 82) 9 - Concept does not apply.
Co-Surgeons (62) 9 - Concept does not apply.
Team Surgery (66) 9 - Concept does not apply.
Diagnostic Imaging Family 99 - Concept Does Not Apply
CLIA Waived (QW) No
APC Status Indicator Conditionally packaged laboratory tests
Type of Service (TOS) 5 - Diagnostic Laboratory
Berenson-Eggers TOS (BETOS) T1H - Lab tests - other (non-Medicare fee schedule)
MUE 2
CCS Clinical Classification 235 - Other Laboratory
59 Distinct procedural service: under certain circumstances, it may be necessary to indicate that a procedure or service was distinct or independent from other non-e/m services performed on the same day. modifier 59 is used to identify procedures/services, other than e/m services, that are not normally reported together, but are appropriate under the circumstances. documentation must support a different session, different procedure or surgery, different site or organ system, separate incision/excision, separate lesion, or separate injury (or area of injury in extensive injuries) not ordinarily encountered or performed on the same day by the same individual. however, when another already established modifier is appropriate it should be used rather than modifier 59. only if no more descriptive modifier is available, and the use of modifier 59 best explains the circumstances, should modifier 59 be used. note: modifier 59 should not be appended to an e/m service. to report a separate and distinct e/m service with a non-e/m service performed on the same date, see modifier 25.
90 Reference (outside) laboratory: when laboratory procedures are performed by a party other than the treating or reporting physician or other qualified health care professional, the procedure may be identified by adding modifier 90 to the usual procedure number.
GA Waiver of liability statement issued as required by payer policy, individual case
GY Item or service statutorily excluded, does not meet the definition of any medicare benefit or, for non-medicare insurers, is not a contract benefit
91 Repeat clinical diagnostic laboratory test: in the course of treatment of the patient, it may be necessary to repeat the same laboratory test on the same day to obtain subsequent (multiple) test results. under these circumstances, the laboratory test performed can be identified by its usual procedure number and the addition of modifier 91. note: this modifier may not be used when tests are rerun to confirm initial results; due to testing problems with specimens or equipment; or for any other reason when a normal, one-time, reportable result is all that is required. this modifier may not be used when other code(s) describe a series of test results (eg, glucose tolerance tests, evocative/suppression testing). this modifier may only be used for laboratory test(s) performed more than once on the same day on the same patient.
XS Separate structure, a service that is distinct because it was performed on a separate organ/structure
XU Unusual non-overlapping service, the use of a service that is distinct because it does not overlap usual components of the main service
Date
Action
Notes
2018-01-01 Changed Long medium and short descriptions changed. AMA guidelines changed.
2008-01-01 Changed Code description changed.
1994-01-01 Added First appearance in code book in 1994.
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