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Official Description

Antibody identification; platelet antibodies

© Copyright 2026 American Medical Association. All rights reserved.

Common Language Description

The CPT® Code 86022 refers to the procedure of antibody identification specifically for platelet antibodies. This test is crucial in the field of immunology and transfusion medicine, as it helps in identifying specific antibodies that target platelets, which are essential components of blood involved in clotting. Platelet antibodies can be either alloantibodies, which are formed in response to foreign platelet antigens, or autoantibodies, which are produced against the body's own platelets. The identification of these antibodies is vital for diagnosing various medical conditions, including autoimmune disorders, which can lead to the destruction of platelets, resulting in thrombocytopenia. Additionally, this test plays a significant role in managing complications related to pregnancy, such as miscarriage, and in monitoring patients who have undergone tissue or organ transplants, where the immune system may react against the transplanted material. The procedure typically involves obtaining a blood sample, which is then analyzed using advanced techniques such as enzyme-linked immunosorbent assay (ELISA) and flow cytometry. These methods allow for the precise detection of antibodies against platelet glycoproteins and Class I human leukocyte antigens (HLA), providing essential information for patient management and treatment decisions.

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