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Official Description

Antibody identification; platelet associated immunoglobulin assay

© Copyright 2026 American Medical Association. All rights reserved.

Common Language Description

The CPT® Code 86023 refers to the procedure known as the antibody identification for platelet associated immunoglobulin assay. This test is crucial in the evaluation of platelet-related disorders, particularly those involving immune responses. It focuses on identifying specific immunoglobulins, namely IgG and IgM, that are associated with platelets. These immunoglobulins can play a significant role in various medical conditions, including thrombocytopenia, which is a condition characterized by low platelet counts. Thrombocytopenia can arise from immune-mediated processes, where the body’s immune system mistakenly targets and destroys its own platelets. The presence of excess IgG and/or IgM platelet associated immunoglobulins can indicate that the thrombocytopenia is of immune origin, suggesting an autoimmune response. Conversely, the absence of these antibodies may suggest that the thrombocytopenia is due to non-immune causes. The test is typically performed using flow cytometry, a sophisticated technique that allows for the precise measurement and analysis of the antibodies present in a blood sample. This assay is essential for clinicians to determine the underlying cause of thrombocytopenia and to guide appropriate treatment strategies.

© Copyright 2026 Coding Ahead. All rights reserved.

1. Indications

The antibody identification for platelet associated immunoglobulin assay (CPT® Code 86023) is indicated for the evaluation of various conditions related to platelet function and immune response. The following are specific indications for performing this test:

  • Thrombocytopenia of Immune Origin This test is utilized to identify excess IgG and/or IgM platelet associated immunoglobulins, which can indicate that the thrombocytopenia is due to an immune-mediated process.
  • Autoimmune Disorders The assay helps in diagnosing conditions where the immune system produces antibodies against the body’s own platelets, leading to decreased platelet counts.
  • Monitoring Post-Transfusion Purpura (PTP) The test can assist in evaluating patients who have experienced PTP, a condition that can occur after blood transfusions due to the development of antibodies against transfused platelets.
  • Neonatal Alloimmune Thrombocytopenia (NATP) This assay is also relevant in cases of NATP, where maternal antibodies target fetal platelets, leading to thrombocytopenia in the newborn.

2. Procedure

The procedure for the antibody identification for platelet associated immunoglobulin assay involves several key steps to ensure accurate results. The following outlines the procedural steps:

  • Step 1: Blood Sample Collection A blood sample is obtained from the patient, which serves as the specimen for the assay. Proper venipuncture techniques are employed to ensure the integrity of the sample.
  • Step 2: Sample Preparation The collected blood sample is processed to isolate the platelets and prepare them for analysis. This may involve centrifugation to separate the plasma and cellular components.
  • Step 3: Flow Cytometry Analysis The prepared sample is subjected to flow cytometry, a technique that allows for the detection and quantification of specific antibodies bound to the platelets. This method provides precise measurements of IgG and IgM levels associated with the platelets.
  • Step 4: Interpretation of Results The results are analyzed to determine the presence or absence of excess platelet associated immunoglobulins. An increase in these immunoglobulins indicates thrombocytopenia of immune origin, while their absence suggests non-immune causes.

3. Post-Procedure

After the antibody identification for platelet associated immunoglobulin assay is completed, the patient may not require any specific post-procedure care. However, it is essential for healthcare providers to review the results in conjunction with clinical findings and other laboratory tests. The interpretation of the results will guide further management and treatment options for the patient, particularly in cases of thrombocytopenia. Follow-up consultations may be necessary to discuss the implications of the test results and to determine the appropriate course of action based on the underlying cause of the patient's condition.

Short Descr IMMUNOGLOBULIN ASSAY
Medium Descr ANTIBODY IDENTIFICATION PLATELET IMMUNOGL ASSAY
Long Descr Antibody identification; platelet associated immunoglobulin assay
Status Code Statutory Exclusion (from MPFS, may be paid under other methodologies)
Global Days XXX - Global Concept Does Not Apply
PC/TC Indicator (26, TC) 9 - Not Applicable
Multiple Procedures (51) 9 - Concept does not apply.
Bilateral Surgery (50) 9 - Concept does not apply.
Physician Supervisions 09 - Concept does not apply.
Assistant Surgeon (80, 82) 9 - Concept does not apply.
Co-Surgeons (62) 9 - Concept does not apply.
Team Surgery (66) 9 - Concept does not apply.
Diagnostic Imaging Family 99 - Concept Does Not Apply
CLIA Waived (QW) No
APC Status Indicator Conditionally packaged laboratory tests
Type of Service (TOS) 5 - Diagnostic Laboratory
Berenson-Eggers TOS (BETOS) T1H - Lab tests - other (non-Medicare fee schedule)
MUE 3
CCS Clinical Classification 235 - Other Laboratory
90 Reference (outside) laboratory: when laboratory procedures are performed by a party other than the treating or reporting physician or other qualified health care professional, the procedure may be identified by adding modifier 90 to the usual procedure number.
26 Professional component: certain procedures are a combination of a physician or other qualified health care professional component and a technical component. when the physician or other qualified health care professional component is reported separately, the service may be identified by adding modifier 26 to the usual procedure number.
59 Distinct procedural service: under certain circumstances, it may be necessary to indicate that a procedure or service was distinct or independent from other non-e/m services performed on the same day. modifier 59 is used to identify procedures/services, other than e/m services, that are not normally reported together, but are appropriate under the circumstances. documentation must support a different session, different procedure or surgery, different site or organ system, separate incision/excision, separate lesion, or separate injury (or area of injury in extensive injuries) not ordinarily encountered or performed on the same day by the same individual. however, when another already established modifier is appropriate it should be used rather than modifier 59. only if no more descriptive modifier is available, and the use of modifier 59 best explains the circumstances, should modifier 59 be used. note: modifier 59 should not be appended to an e/m service. to report a separate and distinct e/m service with a non-e/m service performed on the same date, see modifier 25.
76 Repeat procedure or service by same physician or other qualified health care professional: it may be necessary to indicate that a procedure or service was repeated by the same physician or other qualified health care professional subsequent to the original procedure or service. this circumstance may be reported by adding modifier 76 to the repeated procedure or service. note: this modifier should not be appended to an e/m service.
91 Repeat clinical diagnostic laboratory test: in the course of treatment of the patient, it may be necessary to repeat the same laboratory test on the same day to obtain subsequent (multiple) test results. under these circumstances, the laboratory test performed can be identified by its usual procedure number and the addition of modifier 91. note: this modifier may not be used when tests are rerun to confirm initial results; due to testing problems with specimens or equipment; or for any other reason when a normal, one-time, reportable result is all that is required. this modifier may not be used when other code(s) describe a series of test results (eg, glucose tolerance tests, evocative/suppression testing). this modifier may only be used for laboratory test(s) performed more than once on the same day on the same patient.
GA Waiver of liability statement issued as required by payer policy, individual case
GW Service not related to the hospice patient's terminal condition
GZ Item or service expected to be denied as not reasonable and necessary
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Pre-1990 Added Code added.
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