CPT® Code 86335

The CPT® Code 86335 refers to the procedure of immunofixation electrophoresis (IFE) performed on other bodily fluids, such as urine or cerebrospinal fluid (CSF). This laboratory test is designed to detect and analyze abnormal proteins, the absence of normal proteins, and variations in the levels of specific protein groups within these fluids. The immunofixation electrophoresis technique is particularly valuable in diagnosing a range of medical conditions, including inflammatory disorders, autoimmune diseases, acute or chronic infections, and various kidney and liver disorders. Additionally, it is instrumental in identifying protein-losing conditions and multiple myeloma, a type of blood cancer characterized by the proliferation of abnormal plasma cells. The results obtained from the immunofixation electrophoresis test should be interpreted in conjunction with quantitative immunoglobulin level tests and other relevant clinical or laboratory data to provide a comprehensive understanding of the patient's health status. It is important to note that while CPT® Code 86334 pertains to serum testing via IFE, CPT® Code 86335 specifically addresses the analysis of other fluids, which can yield different diagnostic insights. Notably, this code is frequently utilized for the identification of Beta-2 Transferrin, a protein that is typically absent in serum but can indicate a cerebral spinal fluid leak when detected in other fluids. This diagnostic capability underscores the importance of the immunofixation electrophoresis procedure in clinical practice.