© Copyright 2026 American Medical Association. All rights reserved.
The CPT® Code 86923 refers to a compatibility test performed on each unit of blood using electronic methods. This laboratory test is essential for determining the compatibility between a blood donor and a recipient, ensuring that the transfusion process is safe and effective. Compatibility testing, often known as cross matching (CM), is a critical step in the transfusion process to prevent adverse reactions. The electronic compatibility test is a modern approach that utilizes computer software to assess compatibility without the need for physical mixing of the recipient's plasma or serum with the donor's red blood cells. This method follows a specific algorithm to evaluate compatibility based on the recipient's blood type and antibody history. The procedure requires that the recipient has a negative antibody history, and the current blood sample must also be free of atypical red blood cell antibodies. To ensure accuracy, the recipient's ABO and Rh information is entered into the system by two different technicians, minimizing the risk of human error. The donor unit is identified through a bar code, which is scanned into the computer system to verify the ABO and Rh type of the donor blood. This electronic method enhances the reliability of compatibility testing, providing a safer transfusion experience for patients.
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