CPT® Code 88104

CPT® Code 88104 refers to a specific laboratory test known as cytopathology, which involves the examination of fluid samples, washings, or brushings, excluding those taken from cervical or vaginal sources. This procedure is essential for diagnosing a variety of conditions, including malignant and premalignant diseases, infections, autoimmune disorders, inflammation, immune reactions, cell aging, and amyloidosis. Cytopathology focuses on the microscopic analysis of cells that either naturally exfoliate from body surfaces or can be collected through washing or brushing techniques. The samples analyzed can originate from various bodily fluids, such as sputum, urine, breast discharge, cerebrospinal fluid, pleural fluid, peritoneal fluid, pericardial fluid, joint effusions, vitreous fluid from the eye, skin, and the gastrointestinal tract. To perform the test, a sample is obtained through a separately reportable procedure. The cytopathology process typically involves the smear technique, where the collected sample is spread onto a glass slide and subsequently fixed to preserve the cellular structure. In cases where fluid is tested, the simple filter method is employed, which involves filtering the fluid to isolate the cells, with the sediment then fixed onto a glass slide for examination. A pathologist will meticulously analyze the prepared slide under a microscope and generate a comprehensive written report detailing the findings, which aids in the diagnosis and management of the patient's condition.