CPT® Code 88182

Flow cytometry, cell cycle or DNA analysis, as described by CPT® Code 88182, is a sophisticated laboratory test that employs flow cytometry technology to analyze the cell cycle or DNA content of various cell types. This procedure involves the use of fluorescent dyes that specifically bind to DNA, allowing for the visualization and quantification of cells within a sample. The samples can be derived from a variety of sources, including tissue tumors, body fluids, blood, bone marrow, and urine or bladder washings. Once the cells are stained, they are suspended in a fluid stream and passed through an automated detector. This process generates a DNA histogram or cell cycle profile, which is instrumental in assessing the prognosis of malignant tumors and evaluating products of conception for conditions such as hydatidiform mole. The flow cytometry technique enables the counting and sorting of cells based on specific biomarkers, facilitating the differentiation between normal and tumor cells. It is important to note that the sample for this analysis must be obtained through a separately reportable procedure, and the findings are documented in a written report that details the results of the analysis.