© Copyright 2026 American Medical Association. All rights reserved.
The CPT® Code 90626 refers to an inactivated vaccine specifically designed to protect against the tick-borne encephalitis (TBE) virus. This vaccine is administered intramuscularly in a dosage of 0.25 mL. TBE is a serious viral infection that can lead to significant neurological complications, including muscle weakness, cognitive decline, and in severe cases, permanent paralysis or death. Unlike immune globulins, which offer only temporary, passive immunity, vaccines like this one provide active, long-lasting immunity. They work by introducing altered forms of the virus to the immune system, prompting it to produce its own antibodies. This process enables the body to "remember" how to respond to future exposures to the virus. The vaccine, TICOVAC™, which received approval in the U.S. in 2021, is effective in preventing TBE in both children and adults who are traveling to or living in areas where the virus is prevalent. While TBE is not currently endemic in the United States, it remains a significant health concern in various regions of Europe and Asia. It is important to note that when reporting this code, it is specifically for the vaccine product itself. The administration of the intramuscular injection should be reported separately, with the injection typically given in the arm for adults and in the thigh for children.
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