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Code deleted, see 94729.

Official Description

Membrane diffusion capacity

© Copyright 2026 American Medical Association. All rights reserved.

Common Language Description

The CPT® Code 94725 refers to a test known as the membrane diffusion capacity test, which is specifically designed to assess the lung's ability to transfer gases from the air into the bloodstream. This test involves the patient inhaling a mixture of air that contains a precise, known quantity of carbon monoxide (CO). The primary purpose of this procedure is to measure how much carbon monoxide is absorbed by the lungs and subsequently enters the bloodstream. By comparing the amount of CO inhaled with the amount exhaled, healthcare professionals can evaluate the efficiency of the lung membranes in facilitating gas exchange. This test is crucial for diagnosing and monitoring various pulmonary conditions, as it provides valuable insights into the functionality of the alveoli, the tiny air sacs in the lungs where gas exchange occurs. Understanding the membrane diffusion capacity is essential for determining the overall health of the respiratory system and identifying any potential impairments in gas exchange that may be present in patients with respiratory diseases.

© Copyright 2026 Coding Ahead. All rights reserved.

1. Indications

The membrane diffusion capacity test (CPT® Code 94725) is indicated for various clinical scenarios where assessment of lung function is necessary. The following conditions may warrant the performance of this test:

  • Evaluation of Pulmonary Diseases This test is often utilized in the diagnosis and management of chronic obstructive pulmonary disease (COPD), interstitial lung disease, and pulmonary fibrosis, where gas exchange may be compromised.
  • Assessment of Symptoms Patients presenting with unexplained dyspnea (shortness of breath) or other respiratory symptoms may undergo this test to determine if there is an underlying issue affecting lung function.
  • Preoperative Evaluation The test may be performed as part of a preoperative assessment for patients undergoing thoracic surgery or lung transplantation to evaluate their pulmonary reserve and suitability for surgery.
  • Monitoring Disease Progression For patients with known lung conditions, this test can be used to monitor changes in lung function over time, helping to guide treatment decisions.

2. Procedure

The membrane diffusion capacity test involves several key procedural steps to ensure accurate measurement of lung function. The following outlines the procedure:

  • Preparation of the Patient Prior to the test, the patient is instructed to avoid smoking and certain medications that may affect lung function for a specified period. The healthcare provider will explain the procedure to the patient to ensure understanding and cooperation.
  • Inhalation of the Gas Mixture The patient is then positioned comfortably and instructed to inhale a specific air mixture that contains a known concentration of carbon monoxide. This inhalation is typically done through a mouthpiece or a face mask to ensure accurate delivery of the gas.
  • Measurement of Exhaled Gas After inhalation, the patient is asked to hold their breath for a brief period, allowing the carbon monoxide to diffuse across the alveolar membrane into the bloodstream. Following this, the patient exhales into a collection device, which captures the exhaled air for analysis.
  • Analysis of Results The amount of carbon monoxide inhaled is compared to the amount exhaled. This data is analyzed to determine the membrane diffusion capacity, providing insights into the efficiency of gas exchange in the lungs.

3. Post-Procedure

After the membrane diffusion capacity test is completed, the patient may be monitored briefly to ensure there are no immediate adverse reactions to the inhaled gas mixture. Generally, there are no significant post-procedure restrictions, and patients can resume normal activities unless otherwise advised by their healthcare provider. The results of the test will be interpreted by a qualified professional, who will discuss the findings with the patient and determine any necessary follow-up actions or treatments based on the results.

Short Descr MEMBRANE DIFFUSION CAPACITY
Medium Descr MEMB DIFFUSION CAP
Long Descr Membrane diffusion capacity
Status Code Active Code
Global Days XXX - Global Concept Does Not Apply
PC/TC Indicator (26, TC) 1 - Diagnostic Tests for Radiology Services
Multiple Procedures (51) 0 - No payment adjustment rules for multiple procedures apply.
Bilateral Surgery (50) 0 - 150% payment adjustment for bilateral procedures does NOT apply.
Physician Supervisions 09 - Concept does not apply.
Assistant Surgeon (80, 82) 0 - Payment restriction for assistants at surgery applies to this procedure...
Co-Surgeons (62) 0 - Co-surgeons not permitted for this procedure.
Team Surgery (66) 0 - Team surgeons not permitted for this procedure.
Diagnostic Imaging Family 99 - Concept Does Not Apply
APC Status Indicator Discontinued Code
Type of Service (TOS) 5 - Diagnostic Laboratory
Berenson-Eggers TOS (BETOS) none
MUE Not applicable/unspecified.
CCS Clinical Classification 233 - Laboratory - Chemistry and Hematology
Date
Action
Notes
2012-01-01 Deleted Code deleted, see 94729.
Pre-1990 Added Code added.
Code
Description
Code
Description
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