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Official Description

Ingestion challenge test (sequential and incremental ingestion of test items, eg, food, drug or other substance); initial 120 minutes of testing

© Copyright 2026 American Medical Association. All rights reserved.

Common Language Description

The ingestion challenge test, represented by CPT® Code 95076, is a diagnostic procedure utilized to identify specific allergies through the sequential and incremental ingestion of test items, which may include food, drugs, or other substances. During this test, the physician closely monitors the patient for any allergic reactions that may occur as a result of ingesting these items. The process involves replicating normal food consumption patterns, including the amount and state of the food or substance ingested, to accurately assess the patient's response. The observation period following ingestion is critical, as it typically aligns with the usual time frame between ingestion and the onset of symptoms, which is determined based on the patient's medical history. This code specifically covers the initial 120 minutes of testing, allowing healthcare professionals to document and report the time spent observing the patient for potential allergic reactions. For extended testing beyond the initial period, CPT® Code 95079 should be utilized to report each additional 60 minutes of observation.

© Copyright 2026 Coding Ahead. All rights reserved.

1. Indications

The ingestion challenge test is indicated for patients who require evaluation for specific allergies, particularly when there is a need to determine the patient's reaction to certain foods, drugs, or other substances. This test is typically performed in cases where the patient's history suggests potential allergic responses, and further investigation is necessary to confirm or rule out these allergies.

  • Food Allergies Patients with suspected food allergies may undergo this test to identify specific allergens that trigger adverse reactions.
  • Drug Allergies Individuals who have experienced allergic reactions to medications may be tested to pinpoint the exact drug responsible for the reaction.
  • Other Substances The test can also be used to evaluate reactions to other substances that may not fall under the categories of food or drugs.

2. Procedure

The ingestion challenge test involves several procedural steps to ensure accurate assessment of the patient's allergic responses. The following steps outline the process:

  • Step 1: Patient Preparation Prior to the test, the patient is thoroughly evaluated, and their medical history is reviewed to identify any known allergies or previous reactions. This preparation is crucial for determining the appropriate test items to be ingested.
  • Step 2: Selection of Test Items Based on the patient's history, specific foods, drugs, or substances are selected for the ingestion challenge. These items are chosen to replicate normal consumption patterns and are administered in a controlled manner.
  • Step 3: Ingestion of Test Items The patient ingests the selected test items sequentially and incrementally. The ingestion is closely monitored by the physician to ensure safety and to observe any immediate reactions.
  • Step 4: Observation Period Following ingestion, the patient is observed for a total of 120 minutes. During this time, the physician assesses the patient for any signs of allergic reactions, documenting any symptoms that arise and their timing in relation to ingestion.

3. Post-Procedure

After the ingestion challenge test is completed, the physician will review the observations made during the testing period. If any allergic reactions were noted, further evaluation and management may be necessary based on the severity and type of reaction observed. The patient may be advised on dietary restrictions or avoidance of specific substances identified as allergens. Follow-up appointments may be scheduled to discuss the results and any additional testing or treatment options that may be required.

Short Descr INGEST CHALLENGE INI 120 MIN
Medium Descr INGESTION CHALLENGE TEST INITIAL 120 MINUTES
Long Descr Ingestion challenge test (sequential and incremental ingestion of test items, eg, food, drug or other substance); initial 120 minutes of testing
Status Code Active Code
Global Days XXX - Global Concept Does Not Apply
PC/TC Indicator (26, TC) 0 - Physician Service Code
Multiple Procedures (51) 0 - No payment adjustment rules for multiple procedures apply.
Bilateral Surgery (50) 0 - 150% payment adjustment for bilateral procedures does NOT apply.
Physician Supervisions 09 - Concept does not apply.
Assistant Surgeon (80, 82) 0 - Payment restriction for assistants at surgery applies to this procedure...
Co-Surgeons (62) 0 - Co-surgeons not permitted for this procedure.
Team Surgery (66) 0 - Team surgeons not permitted for this procedure.
Diagnostic Imaging Family 99 - Concept Does Not Apply
APC Status Indicator Procedure or Service, Not Discounted when Multiple
Type of Service (TOS) 1 - Medical Care
Berenson-Eggers TOS (BETOS) T2D - Other tests - other
MUE 1
CCS Clinical Classification 173 - Other diagnostic procedures on skin and subcutaneous tissue

This is a primary code that can be used with these additional add-on codes.

95079 Addon Code MPFS Status: Active Code APC N Ingestion challenge test (sequential and incremental ingestion of test items, eg, food, drug or other substance); each additional 60 minutes of testing (List separately in addition to code for primary procedure)
59 Distinct procedural service: under certain circumstances, it may be necessary to indicate that a procedure or service was distinct or independent from other non-e/m services performed on the same day. modifier 59 is used to identify procedures/services, other than e/m services, that are not normally reported together, but are appropriate under the circumstances. documentation must support a different session, different procedure or surgery, different site or organ system, separate incision/excision, separate lesion, or separate injury (or area of injury in extensive injuries) not ordinarily encountered or performed on the same day by the same individual. however, when another already established modifier is appropriate it should be used rather than modifier 59. only if no more descriptive modifier is available, and the use of modifier 59 best explains the circumstances, should modifier 59 be used. note: modifier 59 should not be appended to an e/m service. to report a separate and distinct e/m service with a non-e/m service performed on the same date, see modifier 25.
GC This service has been performed in part by a resident under the direction of a teaching physician
GA Waiver of liability statement issued as required by payer policy, individual case
25 Significant, separately identifiable evaluation and management service by the same physician or other qualified health care professional on the same day of the procedure or other service: it may be necessary to indicate that on the day a procedure or service identified by a cpt code was performed, the patient's condition required a significant, separately identifiable e/m service above and beyond the other service provided or beyond the usual preoperative and postoperative care associated with the procedure that was performed. a significant, separately identifiable e/m service is defined or substantiated by documentation that satisfies the relevant criteria for the respective e/m service to be reported (see evaluation and management services guidelines for instructions on determining level of e/m service). the e/m service may be prompted by the symptom or condition for which the procedure and/or service was provided. as such, different diagnoses are not required for reporting of the e/m services on the same date. this circumstance may be reported by adding modifier 25 to the appropriate level of e/m service. note: this modifier is not used to report an e/m service that resulted in a decision to perform surgery. see modifier 57 for significant, separately identifiable non-e/m services, see modifier 59.
51 Multiple procedures: when multiple procedures, other than e/m services, physical medicine and rehabilitation services or provision of supplies (eg, vaccines), are performed at the same session by the same individual, the primary procedure or service may be reported as listed. the additional procedure(s) or service(s) may be identified by appending modifier 51 to the additional procedure or service code(s). note: this modifier should not be appended to designated "add-on" codes (see appendix d).
52 Reduced services: under certain circumstances a service or procedure is partially reduced or eliminated at the discretion of the physician or other qualified health care professional. under these circumstances the service provided can be identified by its usual procedure number and the addition of modifier 52, signifying that the service is reduced. this provides a means of reporting reduced services without disturbing the identification of the basic service. note: for hospital outpatient reporting of a previously scheduled procedure/service that is partially reduced or cancelled as a result of extenuating circumstances or those that threaten the well-being of the patient prior to or after administration of anesthesia, see modifiers 73 and 74 (see modifiers approved for asc hospital outpatient use).
76 Repeat procedure or service by same physician or other qualified health care professional: it may be necessary to indicate that a procedure or service was repeated by the same physician or other qualified health care professional subsequent to the original procedure or service. this circumstance may be reported by adding modifier 76 to the repeated procedure or service. note: this modifier should not be appended to an e/m service.
CC Procedure code change (use 'cc' when the procedure code submitted was changed either for administrative reasons or because an incorrect code was filed)
CR Catastrophe/disaster related
GW Service not related to the hospice patient's terminal condition
GX Notice of liability issued, voluntary under payer policy
GY Item or service statutorily excluded, does not meet the definition of any medicare benefit or, for non-medicare insurers, is not a contract benefit
GZ Item or service expected to be denied as not reasonable and necessary
PD Diagnostic or related non diagnostic item or service provided in a wholly owned or operated entity to a patient who is admitted as an inpatient within 3 days
Q6 Service furnished under a fee-for-time compensation arrangement by a substitute physician or by a substitute physical therapist furnishing outpatient physical therapy services in a health professional shortage area, a medically underserved area, or a rural area
SA Nurse practitioner rendering service in collaboration with a physician
XE Separate encounter, a service that is distinct because it occurred during a separate encounter
XS Separate structure, a service that is distinct because it was performed on a separate organ/structure
XU Unusual non-overlapping service, the use of a service that is distinct because it does not overlap usual components of the main service
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