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Official Description

Ingestion challenge test (sequential and incremental ingestion of test items, eg, food, drug or other substance); each additional 60 minutes of testing (List separately in addition to code for primary procedure)

© Copyright 2026 American Medical Association. All rights reserved.

Common Language Description

The ingestion challenge test is a diagnostic procedure used to identify specific allergies by observing the patient's reactions to various test items, which may include foods, drugs, or other substances. During this test, the patient sequentially and incrementally ingests these items under careful medical supervision. The physician closely monitors the patient for any allergic reactions that may occur, which helps in determining the presence of allergies to the ingested substances. The test is designed to replicate normal food consumption, taking into account the amount and state of the food or substance ingested. The observation period following ingestion is critical, as it aligns with the typical time frame for the onset of allergic symptoms based on the patient's medical history. For accurate coding, the initial 120 minutes of the ingestion challenge test is reported using CPT® code 95076, while CPT® code 95079 is utilized to report each additional 60 minutes of testing beyond the initial period.

© Copyright 2026 Coding Ahead. All rights reserved.

1. Indications

The ingestion challenge test is indicated for patients who exhibit symptoms suggestive of food or drug allergies. This test is particularly useful in the following scenarios:

  • Food Allergies Patients with a history of adverse reactions to specific foods may undergo this test to confirm or rule out allergies.
  • Drug Allergies Individuals who have experienced allergic reactions to medications may be tested to identify the specific drug responsible for the reaction.
  • Unexplained Symptoms Patients presenting with unexplained allergic symptoms may require this test to determine potential triggers.

2. Procedure

The ingestion challenge test involves several procedural steps to ensure accurate assessment of the patient's allergic responses. Each step is critical for the safety and effectiveness of the test.

  • Step 1: Patient Preparation Prior to the test, the physician reviews the patient's medical history, including any previous allergic reactions, to determine the appropriate substances for testing. The patient is informed about the procedure, potential risks, and the importance of reporting any symptoms during the test.
  • Step 2: Initial Testing The initial phase of the test involves the patient ingesting a controlled amount of the first test item, which may be a food or drug. This phase is monitored closely for any immediate allergic reactions, typically over a period of 120 minutes, which is reported using CPT® code 95076.
  • Step 3: Incremental Dosing If no significant reactions occur during the initial testing phase, the physician may proceed with incremental dosing of additional test items. Each subsequent ingestion is carefully timed and monitored, with the patient observed for any delayed allergic responses.
  • Step 4: Extended Observation For each additional 60 minutes of testing beyond the initial 120 minutes, CPT® code 95079 is reported. The physician continues to observe the patient for symptoms, documenting any reactions that occur during this extended observation period.

3. Post-Procedure

After the ingestion challenge test, the physician evaluates the patient's reactions and provides appropriate follow-up care based on the findings. Patients may be advised to avoid any identified allergens and may receive instructions on managing allergic reactions. Documentation of the test results and any recommendations for future dietary or medication restrictions is essential for ongoing patient care. Additionally, the physician may schedule follow-up appointments to monitor the patient's condition and address any further concerns related to allergies.

Short Descr INGEST CHALLENGE ADDL 60 MIN
Medium Descr INGESTION CHALLENGE TEST EACH ADDL 60 MINUTES
Long Descr Ingestion challenge test (sequential and incremental ingestion of test items, eg, food, drug or other substance); each additional 60 minutes of testing (List separately in addition to code for primary procedure)
Status Code Active Code
Global Days ZZZ - Code Related to Another Service
PC/TC Indicator (26, TC) 0 - Physician Service Code
Multiple Procedures (51) 0 - No payment adjustment rules for multiple procedures apply.
Bilateral Surgery (50) 0 - 150% payment adjustment for bilateral procedures does NOT apply.
Physician Supervisions 09 - Concept does not apply.
Assistant Surgeon (80, 82) 0 - Payment restriction for assistants at surgery applies to this procedure...
Co-Surgeons (62) 0 - Co-surgeons not permitted for this procedure.
Team Surgery (66) 0 - Team surgeons not permitted for this procedure.
Diagnostic Imaging Family 99 - Concept Does Not Apply
APC Status Indicator Items and Services Packaged into APC Rates
Type of Service (TOS) 1 - Medical Care
Berenson-Eggers TOS (BETOS) T2D - Other tests - other
MUE 2
CCS Clinical Classification 173 - Other diagnostic procedures on skin and subcutaneous tissue

This is an add-on code that must be used in conjunction with one of these primary codes.

95076 MPFS Status: Active Code APC S Ingestion challenge test (sequential and incremental ingestion of test items, eg, food, drug or other substance); initial 120 minutes of testing
59 Distinct procedural service: under certain circumstances, it may be necessary to indicate that a procedure or service was distinct or independent from other non-e/m services performed on the same day. modifier 59 is used to identify procedures/services, other than e/m services, that are not normally reported together, but are appropriate under the circumstances. documentation must support a different session, different procedure or surgery, different site or organ system, separate incision/excision, separate lesion, or separate injury (or area of injury in extensive injuries) not ordinarily encountered or performed on the same day by the same individual. however, when another already established modifier is appropriate it should be used rather than modifier 59. only if no more descriptive modifier is available, and the use of modifier 59 best explains the circumstances, should modifier 59 be used. note: modifier 59 should not be appended to an e/m service. to report a separate and distinct e/m service with a non-e/m service performed on the same date, see modifier 25.
76 Repeat procedure or service by same physician or other qualified health care professional: it may be necessary to indicate that a procedure or service was repeated by the same physician or other qualified health care professional subsequent to the original procedure or service. this circumstance may be reported by adding modifier 76 to the repeated procedure or service. note: this modifier should not be appended to an e/m service.
AQ Physician providing a service in an unlisted health professional shortage area (hpsa)
CR Catastrophe/disaster related
GA Waiver of liability statement issued as required by payer policy, individual case
GC This service has been performed in part by a resident under the direction of a teaching physician
GY Item or service statutorily excluded, does not meet the definition of any medicare benefit or, for non-medicare insurers, is not a contract benefit
GZ Item or service expected to be denied as not reasonable and necessary
PD Diagnostic or related non diagnostic item or service provided in a wholly owned or operated entity to a patient who is admitted as an inpatient within 3 days
XS Separate structure, a service that is distinct because it was performed on a separate organ/structure
XU Unusual non-overlapping service, the use of a service that is distinct because it does not overlap usual components of the main service
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2013-01-01 Added Added
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