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Official Description

Professional services for the supervision of preparation and provision of antigens for allergen immunotherapy, single dose vial(s) (specify number of vials)

© Copyright 2026 American Medical Association. All rights reserved.

Common Language Description

The CPT® Code 95144 refers to the professional services involved in the supervision of the preparation and provision of antigens specifically for allergen immunotherapy. This procedure is performed by an allergist or another qualified supplier who oversees the preparation of single dose vials containing the necessary antigens. These antigens are formulated based on the results obtained from allergy testing services, which are reported separately. The preparation process ensures that the correct dosage of the allergen is accurately formulated and provided to the patient in single dose vials. Each vial is designed to deliver a precise formulation intended for a single injection of the antigen, facilitating a controlled and effective immunotherapy regimen. The total number of single dose vials required for a complete course of immunotherapy is prepared, and the allergist reports the code 95144 for each vial supplied. Typically, the allergist administers the initial dose of the antigen and monitors the patient for any adverse reactions. Following this initial administration, the patient is responsible for taking the remaining single dose vials to another healthcare provider, who will administer the subsequent doses as part of the ongoing treatment plan.

© Copyright 2026 Coding Ahead. All rights reserved.

1. Indications

The procedure associated with CPT® Code 95144 is indicated for patients undergoing allergen immunotherapy. The specific indications for this procedure include:

  • Allergic Rhinitis Patients suffering from allergic rhinitis may require allergen immunotherapy to reduce symptoms associated with allergens such as pollen, dust mites, or pet dander.
  • Allergic Asthma Individuals with allergic asthma may benefit from immunotherapy to help manage their symptoms and reduce the frequency of asthma attacks triggered by allergens.
  • Insect Allergy Patients with a history of severe allergic reactions to insect stings may be candidates for immunotherapy to decrease their sensitivity to these allergens.
  • Allergic Conjunctivitis Those experiencing allergic conjunctivitis may also be treated with allergen immunotherapy to alleviate their symptoms.

2. Procedure

The procedure for CPT® Code 95144 involves several key steps in the preparation and provision of antigens for allergen immunotherapy:

  • Step 1: Allergy Testing Prior to the preparation of antigens, the patient undergoes allergy testing to identify specific allergens that trigger their allergic reactions. This testing is crucial as it provides the necessary data to formulate the appropriate antigens for immunotherapy.
  • Step 2: Preparation of Antigens Based on the results of the allergy testing, the allergist or qualified supplier prepares the antigens. This involves formulating the correct dosage of the allergen into single dose vials, ensuring that each vial contains the precise amount needed for a single injection.
  • Step 3: Supervision of Preparation The allergist supervises the entire preparation process to ensure compliance with safety and quality standards. This supervision is essential to guarantee that the antigens are prepared correctly and are safe for patient use.
  • Step 4: Provision of Single Dose Vials Once the antigens are prepared, the allergist provides the patient with the single dose vials. The total number of vials required for the course of immunotherapy is supplied, and the allergist reports code 95144 for each vial provided.
  • Step 5: Initial Dose Administration The allergist typically administers the first dose of the antigen to the patient in a controlled setting, monitoring for any immediate adverse effects. This initial administration is critical for assessing the patient's tolerance to the allergen.
  • Step 6: Subsequent Doses After the initial dose, the patient is instructed to take the remaining single dose vials to another healthcare provider, who will administer the subsequent doses as part of the ongoing immunotherapy treatment plan.

3. Post-Procedure

Post-procedure care following the administration of the initial dose of allergen immunotherapy is essential for patient safety and monitoring. The allergist observes the patient for any immediate adverse reactions, which may include symptoms such as swelling, itching, or difficulty breathing. Patients are typically advised to report any unusual symptoms or reactions that occur after they have taken the single dose vials to their subsequent healthcare provider. It is also important for patients to adhere to the prescribed schedule for administering the remaining doses to ensure the effectiveness of the immunotherapy. Regular follow-up appointments may be scheduled to assess the patient's response to the treatment and make any necessary adjustments to the immunotherapy regimen.

Short Descr ANTIGEN THERAPY SERVICES
Medium Descr PREPJ& ANTIGEN PRV ALLERGEN IMMUNOTHERAPY 1 DO
Long Descr Professional services for the supervision of preparation and provision of antigens for allergen immunotherapy, single dose vial(s) (specify number of vials)
Status Code Active Code
Global Days XXX - Global Concept Does Not Apply
PC/TC Indicator (26, TC) 0 - Physician Service Code
Multiple Procedures (51) 0 - No payment adjustment rules for multiple procedures apply.
Bilateral Surgery (50) 0 - 150% payment adjustment for bilateral procedures does NOT apply.
Physician Supervisions 09 - Concept does not apply.
Assistant Surgeon (80, 82) 0 - Payment restriction for assistants at surgery applies to this procedure...
Co-Surgeons (62) 0 - Co-surgeons not permitted for this procedure.
Team Surgery (66) 0 - Team surgeons not permitted for this procedure.
Diagnostic Imaging Family 99 - Concept Does Not Apply
APC Status Indicator STV-Packaged Codes
Type of Service (TOS) 1 - Medical Care
Berenson-Eggers TOS (BETOS) M5D - Specialist - other
MUE 30
CCS Clinical Classification 228 - Prophylactic vaccinations and inoculations
59 Distinct procedural service: under certain circumstances, it may be necessary to indicate that a procedure or service was distinct or independent from other non-e/m services performed on the same day. modifier 59 is used to identify procedures/services, other than e/m services, that are not normally reported together, but are appropriate under the circumstances. documentation must support a different session, different procedure or surgery, different site or organ system, separate incision/excision, separate lesion, or separate injury (or area of injury in extensive injuries) not ordinarily encountered or performed on the same day by the same individual. however, when another already established modifier is appropriate it should be used rather than modifier 59. only if no more descriptive modifier is available, and the use of modifier 59 best explains the circumstances, should modifier 59 be used. note: modifier 59 should not be appended to an e/m service. to report a separate and distinct e/m service with a non-e/m service performed on the same date, see modifier 25.
GY Item or service statutorily excluded, does not meet the definition of any medicare benefit or, for non-medicare insurers, is not a contract benefit
XU Unusual non-overlapping service, the use of a service that is distinct because it does not overlap usual components of the main service
25 Significant, separately identifiable evaluation and management service by the same physician or other qualified health care professional on the same day of the procedure or other service: it may be necessary to indicate that on the day a procedure or service identified by a cpt code was performed, the patient's condition required a significant, separately identifiable e/m service above and beyond the other service provided or beyond the usual preoperative and postoperative care associated with the procedure that was performed. a significant, separately identifiable e/m service is defined or substantiated by documentation that satisfies the relevant criteria for the respective e/m service to be reported (see evaluation and management services guidelines for instructions on determining level of e/m service). the e/m service may be prompted by the symptom or condition for which the procedure and/or service was provided. as such, different diagnoses are not required for reporting of the e/m services on the same date. this circumstance may be reported by adding modifier 25 to the appropriate level of e/m service. note: this modifier is not used to report an e/m service that resulted in a decision to perform surgery. see modifier 57 for significant, separately identifiable non-e/m services, see modifier 59.
76 Repeat procedure or service by same physician or other qualified health care professional: it may be necessary to indicate that a procedure or service was repeated by the same physician or other qualified health care professional subsequent to the original procedure or service. this circumstance may be reported by adding modifier 76 to the repeated procedure or service. note: this modifier should not be appended to an e/m service.
GV Attending physician not employed or paid under arrangement by the patient's hospice provider
95 Synchronous telemedicine service rendered via a real-time interactive audio and video telecommunications system: synchronous telemedicine service is defined as a real-time interaction between a physician or other qualified health care professional and a patient who is located at a distant site from the physician or other qualified health care professional. the totality of the communication of information exchanged between the physician or other qualified health care professional and the patient during the course of the synchronous telemedicine service must be of an amount and nature that would be sufficient to meet the key components and/or requirements of the same service when rendered via a face-to-face interaction. modifier 95 may only be appended to the services listed in appendix p. appendix p is the list of cpt codes for services that are typically performed face-to-face, but may be rendered via a real-time (synchronous) interactive audio and video telecommunications system.
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Action
Notes
2013-01-01 Changed Medium Descriptor changed.
2011-01-01 Changed Medium description changed.
2005-01-01 Changed Code description changed.
2002-01-01 Changed Code description changed.
1994-01-01 Added First appearance in code book in 1994.
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