CPT® Code 96406

CPT® Code 96406 refers to the administration of chemotherapy through intralesional injection, specifically when more than seven malignant lesions are treated. This procedure involves the injection of an anti-neoplastic agent directly into one or more malignant lesions located in the skin or subcutaneous tissues. The primary goal of this treatment is to eradicate or significantly reduce the size of these lesions. Prior to the injection, the physician ensures that the skin surrounding the planned injection site is thoroughly cleansed to minimize the risk of infection. Following this preparation, the physician proceeds to inject the anti-neoplastic agent into and around each lesion. If multiple lesions are present, the injection process is repeated for each lesion until all targeted areas have received the treatment. It is important to note that the coding for this procedure is based on the total number of lesions treated rather than the number of injections performed, as a single lesion may require multiple injection sites. For cases involving up to seven lesions, CPT® Code 96405 should be utilized, while CPT® Code 96406 is specifically designated for instances where more than seven lesions are injected.