© Copyright 2026 American Medical Association. All rights reserved.
The CPT® Code 96522 refers to the procedure of refilling and maintaining an implantable pump or reservoir used for drug delivery in a systemic manner, such as through intravenous or intra-arterial routes. This procedure is essential for patients requiring prolonged infusion of various therapeutic agents, including chemotherapy drugs, monoclonal antibodies, biologic response modifiers, and other antineoplastic substances. Prolonged infusion is specifically defined as the administration of these drugs over a duration exceeding eight hours, which necessitates the use of specialized devices like implantable pumps. These pumps are designed to hold a specific volume of the prescribed medication, which is then programmed to be delivered continuously at a predetermined rate over an extended period. During the procedure, healthcare professionals ensure that the pump is functioning correctly and that the medication is being delivered as intended, thereby optimizing treatment efficacy and patient safety. It is important to note that for external portable pumps, a different code, 96521, is utilized, while 96522 is specifically designated for implantable pumps or reservoirs.
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