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Official Description

Handling and/or conveyance of specimen for transfer from the office to a laboratory

© Copyright 2026 American Medical Association. All rights reserved.

Common Language Description

The CPT® Code 99000 refers to the process of handling and/or conveying a specimen for transfer from an office or other healthcare setting to a laboratory. This procedure is essential for ensuring that specimens, which may include blood, tissue, or other biological materials, are properly managed and transported to facilitate accurate laboratory analysis. The handling of specimens involves adhering to specific protocols that dictate how the specimen should be stored prior to transport, ensuring that it remains viable for testing. This may include maintaining the specimen at designated temperatures, such as refrigeration or freezing, to preserve its integrity. Additionally, all safety precautions must be followed during the handling and transportation process to prevent contamination or degradation of the specimen. The successful execution of this procedure is critical for obtaining reliable laboratory results, which are vital for patient diagnosis and treatment.

© Copyright 2026 Coding Ahead. All rights reserved.

1. Indications

The handling and conveyance of specimens as described by CPT® Code 99000 is indicated in various scenarios where biological samples need to be transported for laboratory analysis. The following conditions may warrant this procedure:

  • Specimen Collection When a specimen is collected in an office or healthcare setting and requires transfer to a laboratory for testing.
  • Laboratory Testing When specific laboratory studies are requested that necessitate the analysis of the collected specimen.
  • Protocol Compliance When adherence to laboratory protocols for specimen handling and transport is required to ensure accurate test results.

2. Procedure

The procedure for handling and conveying a specimen involves several critical steps to ensure the specimen's integrity during transport. Each step is essential for compliance with laboratory protocols and for maintaining the quality of the specimen.

  • Step 1: Specimen Collection The first step involves the collection of the specimen in a clinical setting, such as a physician's office. The healthcare provider must follow established protocols for collecting the specimen to minimize contamination and ensure that the sample is representative of the patient's condition.
  • Step 2: Specimen Storage After collection, the specimen must be stored appropriately in the office or the location where it was obtained. This storage must adhere to specific guidelines, which may include maintaining the specimen at a controlled temperature to preserve its viability until transport.
  • Step 3: Preparation for Transport Prior to transport, the specimen is prepared according to the laboratory's requirements. This may involve packaging the specimen securely to prevent leakage or damage during transit, as well as labeling it accurately to ensure proper identification upon arrival at the laboratory.
  • Step 4: Transporting the Specimen The specimen is then transported to the laboratory, following the protocols established for the specific type of specimen. This may include maintaining the specimen at a specific temperature, such as keeping it frozen or refrigerated, to ensure that it remains stable and suitable for testing.
  • Step 5: Adhering to Safety Precautions Throughout the handling and transport process, all safety precautions must be strictly followed. This includes using appropriate personal protective equipment (PPE) and ensuring that the specimen is handled in a manner that minimizes the risk of exposure to potentially infectious materials.

3. Post-Procedure

After the specimen has been successfully transported to the laboratory, it is received and processed according to the laboratory's standard operating procedures. The laboratory staff will verify the specimen's integrity and ensure that it is suitable for the requested tests. Any specific post-procedure care or considerations will depend on the laboratory's protocols and the type of specimen being analyzed. It is crucial that the laboratory receives the specimen in optimal condition to facilitate accurate and timely testing, which is essential for patient diagnosis and treatment.

Short Descr SPECIMEN HANDLING OFFICE-LAB
Medium Descr HANDLG&/OR CONVEY OF SPEC FOR TR OFFICE TO LAB
Long Descr Handling and/or conveyance of specimen for transfer from the office to a laboratory
Status Code Bundled Code
Global Days XXX - Global Concept Does Not Apply
PC/TC Indicator (26, TC) 9 - Not Applicable
Multiple Procedures (51) 9 - Concept does not apply.
Bilateral Surgery (50) 9 - Concept does not apply.
Physician Supervisions 09 - Concept does not apply.
Assistant Surgeon (80, 82) 9 - Concept does not apply.
Co-Surgeons (62) 9 - Concept does not apply.
Team Surgery (66) 9 - Concept does not apply.
Diagnostic Imaging Family 99 - Concept Does Not Apply
APC Status Indicator Non-Covered Service, not paid under OPPS
Type of Service (TOS) 9 - Other Medical Items or Services
Berenson-Eggers TOS (BETOS) T1G - Lab tests - other (Medicare fee schedule)
MUE 0
CCS Clinical Classification 237 - Ancillary Services
59 Distinct procedural service: under certain circumstances, it may be necessary to indicate that a procedure or service was distinct or independent from other non-e/m services performed on the same day. modifier 59 is used to identify procedures/services, other than e/m services, that are not normally reported together, but are appropriate under the circumstances. documentation must support a different session, different procedure or surgery, different site or organ system, separate incision/excision, separate lesion, or separate injury (or area of injury in extensive injuries) not ordinarily encountered or performed on the same day by the same individual. however, when another already established modifier is appropriate it should be used rather than modifier 59. only if no more descriptive modifier is available, and the use of modifier 59 best explains the circumstances, should modifier 59 be used. note: modifier 59 should not be appended to an e/m service. to report a separate and distinct e/m service with a non-e/m service performed on the same date, see modifier 25.
GY Item or service statutorily excluded, does not meet the definition of any medicare benefit or, for non-medicare insurers, is not a contract benefit
CS Cost-sharing waived for specified covid-19 testing-related services that result in and order for or administration of a covid-19 test and/or used for cost-sharing waived preventive services furnished via telehealth in rural health clinics and federally qualified health centers during the covid-19 public health emergency
GA Waiver of liability statement issued as required by payer policy, individual case
90 Reference (outside) laboratory: when laboratory procedures are performed by a party other than the treating or reporting physician or other qualified health care professional, the procedure may be identified by adding modifier 90 to the usual procedure number.
GW Service not related to the hospice patient's terminal condition
CR Catastrophe/disaster related
Q6 Service furnished under a fee-for-time compensation arrangement by a substitute physician or by a substitute physical therapist furnishing outpatient physical therapy services in a health professional shortage area, a medically underserved area, or a rural area
GC This service has been performed in part by a resident under the direction of a teaching physician
XU Unusual non-overlapping service, the use of a service that is distinct because it does not overlap usual components of the main service
JZ Zero drug amount discarded/not administered to any patient
KX Requirements specified in the medical policy have been met
Q5 Service furnished under a reciprocal billing arrangement by a substitute physician or by a substitute physical therapist furnishing outpatient physical therapy services in a health professional shortage area, a medically underserved area, or a rural area
U6 Medicaid level of care 6, as defined by each state
SA Nurse practitioner rendering service in collaboration with a physician
GZ Item or service expected to be denied as not reasonable and necessary
99 Multiple modifiers: under certain circumstances 2 or more modifiers may be necessary to completely delineate a service. in such situations modifier 99 should be added to the basic procedure, and other applicable modifiers may be listed as part of the description of the service.
AQ Physician providing a service in an unlisted health professional shortage area (hpsa)
QW Clia waived test
22 Increased procedural services: when the work required to provide a service is substantially greater than typically required, it may be identified by adding modifier 22 to the usual procedure code. documentation must support the substantial additional work and the reason for the additional work (ie, increased intensity, time, technical difficulty of procedure, severity of patient's condition, physical and mental effort required). note: this modifier should not be appended to an e/m service.
95 Synchronous telemedicine service rendered via a real-time interactive audio and video telecommunications system: synchronous telemedicine service is defined as a real-time interaction between a physician or other qualified health care professional and a patient who is located at a distant site from the physician or other qualified health care professional. the totality of the communication of information exchanged between the physician or other qualified health care professional and the patient during the course of the synchronous telemedicine service must be of an amount and nature that would be sufficient to meet the key components and/or requirements of the same service when rendered via a face-to-face interaction. modifier 95 may only be appended to the services listed in appendix p. appendix p is the list of cpt codes for services that are typically performed face-to-face, but may be rendered via a real-time (synchronous) interactive audio and video telecommunications system.
RT Right side (used to identify procedures performed on the right side of the body)
25 Significant, separately identifiable evaluation and management service by the same physician or other qualified health care professional on the same day of the procedure or other service: it may be necessary to indicate that on the day a procedure or service identified by a cpt code was performed, the patient's condition required a significant, separately identifiable e/m service above and beyond the other service provided or beyond the usual preoperative and postoperative care associated with the procedure that was performed. a significant, separately identifiable e/m service is defined or substantiated by documentation that satisfies the relevant criteria for the respective e/m service to be reported (see evaluation and management services guidelines for instructions on determining level of e/m service). the e/m service may be prompted by the symptom or condition for which the procedure and/or service was provided. as such, different diagnoses are not required for reporting of the e/m services on the same date. this circumstance may be reported by adding modifier 25 to the appropriate level of e/m service. note: this modifier is not used to report an e/m service that resulted in a decision to perform surgery. see modifier 57 for significant, separately identifiable non-e/m services, see modifier 59.
33 Preventive services: when the primary purpose of the service is the delivery of an evidence based service in accordance with a us preventive services task force a or b rating in effect and other preventive services identified in preventive services mandates (legislative or regulatory), the service may be identified by adding 33 to the procedure. for separately reported services specifically identified as preventive, the modifier should not be used.
51 Multiple procedures: when multiple procedures, other than e/m services, physical medicine and rehabilitation services or provision of supplies (eg, vaccines), are performed at the same session by the same individual, the primary procedure or service may be reported as listed. the additional procedure(s) or service(s) may be identified by appending modifier 51 to the additional procedure or service code(s). note: this modifier should not be appended to designated "add-on" codes (see appendix d).
76 Repeat procedure or service by same physician or other qualified health care professional: it may be necessary to indicate that a procedure or service was repeated by the same physician or other qualified health care professional subsequent to the original procedure or service. this circumstance may be reported by adding modifier 76 to the repeated procedure or service. note: this modifier should not be appended to an e/m service.
77 Repeat procedure by another physician or other qualified health care professional: it may be necessary to indicate that a basic procedure or service was repeated by another physician or other qualified health care professional subsequent to the original procedure or service. this circumstance may be reported by adding modifier 77 to the repeated procedure or service. note: this modifier should not be appended to an e/m service.
79 Unrelated procedure or service by the same physician or other qualified health care professional during the postoperative period: the individual may need to indicate that the performance of a procedure or service during the postoperative period was unrelated to the original procedure. this circumstance may be reported by using modifier 79. (for repeat procedures on the same day, see modifier 76.)
93 Synchronous telemedicine service rendered via telephone or other real-time interactive audio-only telecommunications system : synchronous telemedicine service is defined as a real-time interaction between a physician or other qualified health care professional and a patient who is located away at a distant site from the physician or other qualified health care professional. the totality of the communication of information exchanged between the physician or other qualified health care professional and the patient during the course of the synchronous telemedicine service must be of an amount and nature that is sufficient to meet the key components and/or requirements of the same service when rendered via a face-to-face interaction.
CC Procedure code change (use 'cc' when the procedure code submitted was changed either for administrative reasons or because an incorrect code was filed)
FP Service provided as part of family planning program
GE This service has been performed by a resident without the presence of a teaching physician under the primary care exception
GF Non-physician (e.g. nurse practitioner (np), certified registered nurse anesthetist (crna), certified registered nurse (crn), clinical nurse specialist (cns), physician assistant (pa)) services in a critical access hospital
GP Services delivered under an outpatient physical therapy plan of care
GS Dosage of erythropoietin stimulating agent has been reduced and maintained in response to hematocrit or hemoglobin level
GV Attending physician not employed or paid under arrangement by the patient's hospice provider
GX Notice of liability issued, voluntary under payer policy
HO Masters degree level
LT Left side (used to identify procedures performed on the left side of the body)
NU New equipment
PD Diagnostic or related non diagnostic item or service provided in a wholly owned or operated entity to a patient who is admitted as an inpatient within 3 days
Q1 Routine clinical service provided in a clinical research study that is in an approved clinical research study
QJ Services/items provided to a prisoner or patient in state or local custody, however the state or local government, as applicable, meets the requirements in 42 cfr 411.4 (b)
T1 Left foot, second digit
TD Rn
UD Medicaid level of care 13, as defined by each state
UG Services provided in the afternoon
X1 Continuous/broad services: for reporting services by clinicians, who provide the principal care for a patient, with no planned endpoint of the relationship; services in this category represent comprehensive care, dealing with the entire scope of patient problems, either directly or in a care coordination role; reporting clinician service examples include, but are not limited to: primary care, and clinicians providing comprehensive care to patients in addition to specialty care
XS Separate structure, a service that is distinct because it was performed on a separate organ/structure
Date
Action
Notes
2013-01-01 Changed Description Changed
Pre-1990 Added Code added.
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