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Official Description

each separate/additional lesion (List separately in addition to code for primary procedure)

© Copyright 2026 American Medical Association. All rights reserved.

Common Language Description

The CPT® Code 11101 is utilized for the biopsy of each separate or additional lesion beyond the primary procedure. This code is specifically designated for instances where multiple lesions are biopsied during a single patient encounter. The procedure involves the physician carefully cleansing the lesion, administering a local anesthetic to minimize discomfort, and then excising all or part of the lesion using a scalpel. The excised tissue is subsequently sent to a laboratory for histologic examination, which is essential for diagnosing various skin, subcutaneous, or mucous membrane conditions. After the biopsy, the site may be closed with sutures or left open to heal naturally, depending on the clinical judgment of the physician. It is important to note that CPT® Code 11100 should be used for the biopsy of a single lesion, while CPT® Code 11101 is reserved for each additional lesion that is biopsied during the same session.

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