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Official Description

Endoscopic retrograde cholangiopancreatography (ERCP); with pressure measurement of sphincter of Oddi

© Copyright 2026 American Medical Association. All rights reserved.

Common Language Description

Endoscopic retrograde cholangiopancreatography (ERCP) is a specialized medical procedure that combines endoscopy and fluoroscopy to diagnose and treat conditions related to the bile ducts, pancreatic duct, and gallbladder. During this procedure, an endoscope—a flexible tube equipped with a camera and light—is inserted through the esophagus and stomach, advancing into the duodenum, specifically to the ampulla of Vater, where the pancreatic duct and common bile duct converge. This location is critical as it allows for the visualization and intervention of both the biliary and pancreatic systems. In the case of CPT® Code 43263, the procedure includes a pressure measurement of the sphincter of Oddi, which is a muscular valve that regulates the flow of bile and pancreatic secretions into the duodenum. The measurement of the sphincter’s pressure is essential for assessing its function and diagnosing potential disorders, such as sphincter of Oddi dysfunction. The procedure involves the use of contrast dye, which is injected into the ducts to enhance visualization during X-ray imaging, allowing healthcare professionals to identify any obstructions, stones, or abnormalities within the biliary and pancreatic systems.

© Copyright 2026 Coding Ahead. All rights reserved.

1. Indications

Endoscopic retrograde cholangiopancreatography (ERCP) with pressure measurement of the sphincter of Oddi is indicated for various clinical scenarios where assessment of the biliary and pancreatic systems is necessary. The following conditions may warrant the performance of this procedure:

  • Suspected Sphincter of Oddi Dysfunction - Patients presenting with symptoms such as abdominal pain, jaundice, or pancreatitis may require evaluation of the sphincter of Oddi's function.
  • Biliary Obstruction - ERCP is indicated for patients with suspected or confirmed obstructions in the bile duct, which may be caused by gallstones, tumors, or strictures.
  • Cholestasis - This condition, characterized by reduced bile flow, may necessitate ERCP to identify and address underlying causes.
  • Pancreatitis - In cases of acute or recurrent pancreatitis, ERCP can help determine if there is a biliary component contributing to the condition.

2. Procedure

The procedure of endoscopic retrograde cholangiopancreatography (ERCP) with pressure measurement of the sphincter of Oddi involves several critical steps to ensure accurate diagnosis and treatment. The following outlines the procedural steps:

  • Step 1: Patient Preparation - Prior to the procedure, the patient is typically advised to fast for several hours. Sedation is administered to ensure comfort during the procedure.
  • Step 2: Endoscope Insertion - An endoscope is carefully inserted through the mouth, passing through the esophagus and stomach, and is advanced into the duodenum until it reaches the ampulla of Vater.
  • Step 3: Cannulation of the Ampulla - A smaller catheter is introduced through the endoscope, and the ampulla of Vater is cannulated to access the common bile duct and pancreatic duct.
  • Step 4: Contrast Injection - Contrast dye is injected through the catheter into the ducts, allowing for visualization of the biliary and pancreatic systems via X-ray imaging.
  • Step 5: Pressure Measurement - A manometer is utilized to measure the pressure of the sphincter of Oddi, providing critical information regarding its function and potential dysfunction.
  • Step 6: Additional Interventions - If necessary, further interventions such as stone removal or stent placement may be performed during the procedure.

3. Post-Procedure

After the completion of the ERCP with pressure measurement, patients are typically monitored in a recovery area until the effects of sedation wear off. It is common for patients to experience some discomfort, such as bloating or cramping, which usually resolves within a few hours. Patients may be advised to gradually resume normal activities and diet, depending on their individual recovery. Follow-up appointments may be scheduled to discuss the results of the procedure and any further treatment options if necessary. It is important for patients to report any unusual symptoms, such as fever, severe abdominal pain, or jaundice, to their healthcare provider promptly.

Short Descr ERCP SPHINCTER PRESSURE MEAS
Medium Descr ERCP W/PRESSURE MEASUREMENT SPHINCTER OF ODDI
Long Descr Endoscopic retrograde cholangiopancreatography (ERCP); with pressure measurement of sphincter of Oddi
Status Code Active Code
Global Days 000 - Endoscopic or Minor Procedure
PC/TC Indicator (26, TC) 0 - Physician Service Code
Multiple Procedures (51) 3 - Special payment adjustment rules for multiple endoscopic procedures apply.
Bilateral Surgery (50) 0 - 150% payment adjustment for bilateral procedures does NOT apply.
Physician Supervisions 09 - Concept does not apply.
Assistant Surgeon (80, 82) 1 - Statutory payment restriction for assistants at surgery applies to this procedure...
Co-Surgeons (62) 0 - Co-surgeons not permitted for this procedure.
Team Surgery (66) 0 - Team surgeons not permitted for this procedure.
Endoscopic Base Code 43260  Endoscopic retrograde cholangiopancreatography (ERCP); diagnostic, including collection of specimen(s) by brushing or washing, when performed (separate procedure)
Diagnostic Imaging Family 99 - Concept Does Not Apply
APC Status Indicator Hospital Part B services paid through a comprehensive APC
ASC Payment Indicator Surgical procedure on ASC list in CY 2007; payment based on OPPS relative payment weight.
Type of Service (TOS) 2 - Surgery
Berenson-Eggers TOS (BETOS) P8B - Endoscopy - upper gastrointestinal
MUE 1
CCS Clinical Classification 82 - Endoscopic retrograde cannulation of pancreas (ERCP)

This is a primary code that can be used with these additional add-on codes.

0397T Addon Code MPFS Status: Carrier Priced APC N ASC N1 Endoscopic retrograde cholangiopancreatography (ERCP), with optical endomicroscopy (List separately in addition to code for primary procedure)
43273 Addon Code MPFS Status: Active Code APC N ASC N1 CPT Assistant Article Illustration for Code Endoscopic cannulation of papilla with direct visualization of pancreatic/common bile duct(s) (List separately in addition to code(s) for primary procedure)
51 Multiple procedures: when multiple procedures, other than e/m services, physical medicine and rehabilitation services or provision of supplies (eg, vaccines), are performed at the same session by the same individual, the primary procedure or service may be reported as listed. the additional procedure(s) or service(s) may be identified by appending modifier 51 to the additional procedure or service code(s). note: this modifier should not be appended to designated "add-on" codes (see appendix d).
59 Distinct procedural service: under certain circumstances, it may be necessary to indicate that a procedure or service was distinct or independent from other non-e/m services performed on the same day. modifier 59 is used to identify procedures/services, other than e/m services, that are not normally reported together, but are appropriate under the circumstances. documentation must support a different session, different procedure or surgery, different site or organ system, separate incision/excision, separate lesion, or separate injury (or area of injury in extensive injuries) not ordinarily encountered or performed on the same day by the same individual. however, when another already established modifier is appropriate it should be used rather than modifier 59. only if no more descriptive modifier is available, and the use of modifier 59 best explains the circumstances, should modifier 59 be used. note: modifier 59 should not be appended to an e/m service. to report a separate and distinct e/m service with a non-e/m service performed on the same date, see modifier 25.
CC Procedure code change (use 'cc' when the procedure code submitted was changed either for administrative reasons or because an incorrect code was filed)
Date
Action
Notes
2017-01-01 Changed Moderate (Conscious) Sedation flag removed. See new Moderate Sedation category.
2014-01-01 Changed Description Changed
2002-01-01 Changed Code description changed.
Pre-1990 Added Code added.
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