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Official Description

Radiopharmaceutical localization of tumor, inflammatory process or distribution of radiopharmaceutical agent(s) (includes vascular flow and blood pool imaging, when performed); planar, single area (eg, head, neck, chest, pelvis), single day imaging

© Copyright 2026 American Medical Association. All rights reserved.

Common Language Description

The CPT® Code 78800 refers to a diagnostic procedure known as radiopharmaceutical localization, which is utilized to identify tumors or inflammatory processes within the body. This procedure employs molecular imaging techniques, specifically scintigraphy, which involves the use of a radiolabeled isotope tracer. The primary purpose of this imaging is to detect the presence of inflammation or tumors, even in their early stages, by observing the distribution of these radiopharmaceutical agents in the body. The isotope tracer is designed to bind to specific cells, such as those involved in inflammatory responses, or to target particular organs based on their physiological functions. To initiate the procedure, an intravenous line is established, allowing for the direct injection of the radiolabeled isotope tracer into the patient's circulatory system. Alternatively, a blood sample may be drawn, processed to separate the white or red blood cells, and then tagged with the isotope tracer before being reintroduced into the patient. In some cases, radioactive agents may also be administered through inhalation or ingestion, depending on the specific requirements of the imaging study. Once the tracer is in the body, it circulates and localizes in areas of tumorous or inflamed tissue. The patient is then positioned on an imaging table, and a gamma camera is centered over the targeted area for examination. Scanning is conducted at predetermined intervals, capturing the radioactive energy emitted from the tracer, which is subsequently converted into images. This imaging may include blood pool imaging, which visualizes the flow of the radioactive tracer through the area of interest. The CPT® Code 78800 specifically applies to planar imaging of a single area, such as the head, neck, chest, or pelvis, conducted on a single day. For imaging of multiple areas or over multiple days, different CPT codes are applicable, such as 78801 and 78802. The physician is responsible for interpreting the results of the study and providing a comprehensive written report detailing the findings.

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