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Official Description

Radiopharmaceutical localization of tumor, inflammatory process or distribution of radiopharmaceutical agent(s) (includes vascular flow and blood pool imaging, when performed); planar, whole body, requiring 2 or more days imaging

© Copyright 2026 American Medical Association. All rights reserved.

Common Language Description

The CPT® Code 78804 refers to a diagnostic procedure known as radiopharmaceutical localization, which is utilized to identify tumors, inflammatory processes, or the distribution of radiopharmaceutical agents within the body. This procedure employs molecular imaging techniques, specifically scintigraphy, which utilizes a radiolabeled isotope tracer. The primary objective of this imaging is to detect inflammation and/or neoplastic growths, even in their early stages. The radiopharmaceutical agent is designed to attach to specific cells, such as those involved in inflammation or to target particular organs based on their physiological functions. To initiate the procedure, an intravenous line is established, allowing for the direct injection of the radiolabeled isotope tracer into the patient's circulatory system. Alternatively, a blood sample may be drawn, processed to separate the white or red blood cells, and then tagged with the isotope tracer before being reintroduced into the patient. In some cases, radioactive agents may also be administered through inhalation or ingestion, depending on the target area for imaging. Once the tracer is introduced into the body, it circulates and binds to or becomes localized in areas of tumorous or inflamed tissue. The patient is then positioned on an imaging table, and a gamma camera is centered over the area of interest. Scanning is conducted at predetermined intervals, capturing the radioactive energy emitted from the tracer, which is subsequently converted into images. This specific code encompasses planar imaging of the entire body, which necessitates imaging over a span of two or more days. Planar imaging results in a static, two-dimensional representation of the area being examined, and the physician is responsible for interpreting the results and generating a comprehensive written report detailing the findings.

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