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Official Description

Fibrin degradation products, D-dimer; quantitative

© Copyright 2026 American Medical Association. All rights reserved.

Common Language Description

The CPT® Code 85379 refers to the quantitative measurement of fibrin degradation products, specifically D-dimer. This test is crucial in the clinical setting as it aids in ruling out the presence of a thrombus, which is a blood clot that can obstruct blood flow. D-dimer testing is particularly significant in evaluating conditions associated with hypercoagulability, where there is an increased tendency for blood to clot. The test's negative predictive value is a key feature; a negative result suggests that there are no elevated levels of fibrin degradation products in the specimen, indicating a lower likelihood of thrombotic events. Conversely, a positive result signifies an abnormally high concentration of these degradation products, which may suggest the presence of a thrombus. D-dimer testing is instrumental in diagnosing various medical conditions, including deep vein thrombophlebitis, pulmonary embolism, and stroke. Additionally, it plays a role in assessing hypercoagulability, which can predispose patients to the formation of blood clots. The test is also utilized in the diagnosis and management of disseminated intravascular coagulation (DIC), a serious condition characterized by the widespread activation of the clotting process. The quantitative nature of the test, as indicated by CPT® Code 85379, provides precise levels of fibrin degradation products, allowing for more accurate clinical decision-making. In contrast, related codes such as 85378 and 85380 pertain to qualitative and semiquantitative testing methodologies, which differ in sensitivity and specificity. Overall, the D-dimer test is a vital tool in the diagnostic arsenal for conditions related to thrombosis and coagulation disorders.

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