CPT® Code 85380

Fibrin degradation products, D-dimer; ultrasensitive (eg, for evaluation for venous thromboembolism), qualitative or semiquantitative

The CPT® Code 85380 refers to the testing of fibrin degradation products, specifically the D-dimer, using an ultrasensitive method. This test is crucial in the evaluation of venous thromboembolism, which includes conditions such as deep vein thrombosis and pulmonary embolism. The D-dimer test serves as a valuable diagnostic tool, particularly in ruling out the presence of a thrombus, which is a blood clot that can obstruct blood flow. A negative result from this test indicates that there are no elevated levels of fibrin degradation products in the specimen, suggesting that a thrombus is unlikely. Conversely, a positive result signifies an abnormally high level of these degradation products, which may suggest the presence of a thrombus. Additionally, D-dimer testing is utilized to assess hypercoagulability, a condition that increases the risk of blood clots, and to aid in the diagnosis of disseminated intravascular coagulation (DIC). This condition is characterized by the widespread activation of the clotting process in the blood vessels, leading to the formation of small blood clots throughout the body. The D-dimer test can also be instrumental in monitoring the effectiveness of treatment for DIC. It is important to note that there are different methodologies for D-dimer testing. The CPT® Code 85379 is used for quantitative testing, which provides a specific level of fibrin degradation products in the specimen. In contrast, CPT® Codes 85378 and 85380 are designated for qualitative and semiquantitative testing, respectively. Code 85380 specifically refers to ultrasensitive testing, which is designed to deliver rapid and highly accurate results due to its enhanced sensitivity compared to standard testing methods.