CPT® Code 85635

The Reptilase test, identified by CPT® Code 85635, is a specialized laboratory procedure utilized to assess the clotting time of blood. This test is particularly significant in the context of coagulation studies, as it serves as a follow-up to the thrombin time test. The primary purpose of the Reptilase test is to determine whether heparin is influencing the clotting process, which can lead to prolonged clotting times. In cases where heparin is present, the Reptilase test typically yields normal results, indicating that the clotting mechanism is functioning properly despite the presence of heparin. Conversely, if the results show a prolonged clotting time, this may suggest underlying issues such as a deficiency in fibrinogen, abnormalities in fibrinogen due to liver disease, or the presence of lupus anticoagulants in the plasma. The procedure involves the addition of reptilase to citrated blood plasma, followed by the measurement of the rate at which fibrin clots form, providing critical information for diagnosing and managing coagulation disorders.