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Official Description

Skin test; candida

© Copyright 2026 American Medical Association. All rights reserved.

Common Language Description

A candida skin test is a diagnostic procedure utilized primarily to assess the immune response of an individual, particularly in the context of delayed type hypersensitivity reactions. This test serves as an anergy control, which is crucial for interpreting the results of tuberculin skin testing, especially in patients whose cellular immunity may be compromised. In such cases, individuals may exhibit a false negative result during tuberculosis (TB) testing, complicating the diagnostic process. The candida skin test helps to differentiate between a true negative reaction to the TB test and a false negative due to an impaired immune response. Typically, when a person's immune system is functioning adequately, exposure to candida will elicit a positive skin test response. Therefore, a positive result in the candida skin test indicates that the immune system is likely intact, allowing healthcare providers to rule out an underlying compromised immune system as a contributing factor for a negative reaction to the PPD skin test. This distinction is vital for accurate diagnosis and subsequent management of potential TB infections.

© Copyright 2026 Coding Ahead. All rights reserved.

1. Indications

The candida skin test is indicated for use in specific clinical scenarios where assessing the immune response is critical. The following conditions warrant the performance of this test:

  • Compromised Cellular Immunity The test is performed in patients who may have a compromised immune system, which can lead to inaccurate results in other skin tests, such as the tuberculin skin test.
  • Evaluation of Delayed Type Hypersensitivity It is utilized to evaluate delayed type hypersensitivity responses, particularly in the context of tuberculosis screening.
  • False Negative Tuberculin Test The test is indicated when a patient has a negative reaction to a PPD skin test, and there is a need to determine if the negative result is due to anergy.

2. Procedure

The procedure for administering the candida skin test involves several key steps to ensure accurate results and patient safety. The following outlines the procedural steps:

  • Step 1: Preparation The healthcare provider prepares the necessary materials, including the candida antigen, syringes, and alcohol swabs. The patient’s medical history is reviewed to confirm the indication for the test and to check for any contraindications.
  • Step 2: Administration The candida antigen is injected intradermally, typically on the forearm. The injection site is cleansed with an alcohol swab prior to administration to minimize the risk of infection.
  • Step 3: Observation After the injection, the patient is instructed to return for evaluation of the test results, usually within 48 to 72 hours. The healthcare provider will assess the injection site for any signs of a reaction.
  • Step 4: Interpretation The results are interpreted based on the size of the induration at the injection site. A positive reaction indicates a functioning immune response, while a negative reaction may suggest an impaired immune system.

3. Post-Procedure

Post-procedure care for the candida skin test is minimal but important for ensuring patient comfort and accurate interpretation of results. Patients are advised to keep the injection site clean and dry, avoiding any topical applications that could interfere with the test results. They should also be informed about potential reactions, such as redness or swelling at the injection site, which are common and typically resolve without intervention. Patients are encouraged to return to the healthcare provider for evaluation of the test results within the specified timeframe, as timely assessment is crucial for accurate diagnosis and management of any underlying conditions.

Short Descr SKIN TEST CANDIDA
Medium Descr SKIN TEST CANDIDA
Long Descr Skin test; candida
Status Code Carriers Price the Code
Global Days XXX - Global Concept Does Not Apply
PC/TC Indicator (26, TC) 3 - Technical Component Only Code
Multiple Procedures (51) 0 - No payment adjustment rules for multiple procedures apply.
Bilateral Surgery (50) 0 - 150% payment adjustment for bilateral procedures does NOT apply.
Physician Supervisions 09 - Concept does not apply.
Assistant Surgeon (80, 82) 0 - Payment restriction for assistants at surgery applies to this procedure...
Co-Surgeons (62) 0 - Co-surgeons not permitted for this procedure.
Team Surgery (66) 0 - Team surgeons not permitted for this procedure.
Diagnostic Imaging Family 99 - Concept Does Not Apply
APC Status Indicator STV-Packaged Codes
Type of Service (TOS) 5 - Diagnostic Laboratory
Berenson-Eggers TOS (BETOS) T1H - Lab tests - other (non-Medicare fee schedule)
MUE 1
CCS Clinical Classification 235 - Other Laboratory
XE Separate encounter, a service that is distinct because it occurred during a separate encounter
Date
Action
Notes
2011-01-01 Changed Short description changed.
1993-01-01 Added First appearance in code book in 1993.
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Description
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Description
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