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Official Description

Culture, typing; gas liquid chromatography (GLC) or high pressure liquid chromatography (HPLC) method

© Copyright 2026 American Medical Association. All rights reserved.

Common Language Description

The CPT® Code 87143 refers to a laboratory procedure known as culture typing, which utilizes advanced analytical techniques such as gas liquid chromatography (GLC) or high pressure liquid chromatography (HPLC). In this procedure, a blood serum sample is first vaporized into a gas form, allowing for the separation and analysis of various substances present in the sample. This method is particularly effective in identifying specific components within the serum that may be indicative of certain conditions or infections. Alternatively, the high pressure liquid chromatography method involves running the liquid sample through a machine under high pressure, which effectively filters and separates the different components for further identification. Both techniques are crucial in clinical diagnostics, providing valuable information that aids in the understanding of a patient's health status and guiding subsequent treatment decisions.

© Copyright 2026 Coding Ahead. All rights reserved.

1. Indications

The procedure associated with CPT® Code 87143 is indicated for the analysis of blood serum samples to identify specific substances that may be present. This analysis is essential in various clinical scenarios, including:

  • Identification of Infections The procedure is utilized to detect and identify pathogens or infectious agents present in the blood serum, which can assist in diagnosing infections.
  • Monitoring Treatment Efficacy It is used to evaluate the effectiveness of ongoing treatments by analyzing changes in the serum composition over time.
  • Research Purposes The procedure may also be employed in research settings to study the biochemical composition of serum in various health conditions.

2. Procedure

The procedure for CPT® Code 87143 involves specific steps to ensure accurate analysis of the blood serum sample. The following outlines the procedural steps:

  • Sample Collection A blood serum sample is collected from the patient, ensuring that proper collection techniques are followed to avoid contamination and ensure the integrity of the sample.
  • Sample Preparation The collected serum is prepared for analysis, which may involve processes such as centrifugation to separate the serum from blood cells, followed by the appropriate treatment to vaporize the sample for GLC or to prepare it for HPLC.
  • Gas Liquid Chromatography (GLC) In the GLC method, the vaporized serum sample is introduced into a chromatographic system where it is separated into its individual components based on their chemical properties. The machine analyzes these components, providing a detailed profile of the substances present in the serum.
  • High Pressure Liquid Chromatography (HPLC) Alternatively, if the HPLC method is employed, the liquid serum sample is subjected to high pressure as it passes through a chromatographic column. This process filters out different components, allowing for their identification and quantification.
  • Data Analysis After the chromatography process, the results are analyzed to identify the various substances present in the serum. This data is crucial for making informed clinical decisions.

3. Post-Procedure

Post-procedure care for CPT® Code 87143 typically involves monitoring the patient for any immediate reactions to the blood draw, although the procedure itself is non-invasive following the sample collection. The results from the chromatography analysis are usually compiled and reported to the healthcare provider, who will interpret the findings in the context of the patient's clinical picture. Depending on the results, further diagnostic testing or treatment may be recommended. It is important for healthcare providers to communicate the results to the patient and discuss any necessary follow-up actions based on the findings.

Short Descr CULTURE TYPING GLC/HPLC
Medium Descr CULTURE TYPING GAS/HIGH PRES LIQ CHROMATOGRAPHY
Long Descr Culture, typing; gas liquid chromatography (GLC) or high pressure liquid chromatography (HPLC) method
Status Code Statutory Exclusion (from MPFS, may be paid under other methodologies)
Global Days XXX - Global Concept Does Not Apply
PC/TC Indicator (26, TC) 9 - Not Applicable
Multiple Procedures (51) 9 - Concept does not apply.
Bilateral Surgery (50) 9 - Concept does not apply.
Physician Supervisions 09 - Concept does not apply.
Assistant Surgeon (80, 82) 9 - Concept does not apply.
Co-Surgeons (62) 9 - Concept does not apply.
Team Surgery (66) 9 - Concept does not apply.
Diagnostic Imaging Family 99 - Concept Does Not Apply
CLIA Waived (QW) No
APC Status Indicator Conditionally packaged laboratory tests
Type of Service (TOS) 5 - Diagnostic Laboratory
Berenson-Eggers TOS (BETOS) T1H - Lab tests - other (non-Medicare fee schedule)
MUE 2
CCS Clinical Classification 206 - Microscopic examination (bacterial smear, culture, toxicology)
59 Distinct procedural service: under certain circumstances, it may be necessary to indicate that a procedure or service was distinct or independent from other non-e/m services performed on the same day. modifier 59 is used to identify procedures/services, other than e/m services, that are not normally reported together, but are appropriate under the circumstances. documentation must support a different session, different procedure or surgery, different site or organ system, separate incision/excision, separate lesion, or separate injury (or area of injury in extensive injuries) not ordinarily encountered or performed on the same day by the same individual. however, when another already established modifier is appropriate it should be used rather than modifier 59. only if no more descriptive modifier is available, and the use of modifier 59 best explains the circumstances, should modifier 59 be used. note: modifier 59 should not be appended to an e/m service. to report a separate and distinct e/m service with a non-e/m service performed on the same date, see modifier 25.
Date
Action
Notes
2011-01-01 Changed Short description changed.
2001-01-01 Changed Code description changed.
Pre-1990 Added Code added.
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