CPT® Code 87150

Culture, typing; identification by nucleic acid (DNA or RNA) probe, amplified probe technique, per culture or isolate, each organism probed

The CPT® Code 87150 refers to a laboratory procedure that involves the culture and identification of microorganisms, such as bacteria, viruses, fungi, or parasites, using advanced nucleic acid probe techniques. This process allows for the definitive identification of the microorganism to the genus or species level. Initially, a culture is performed to achieve a presumptive identification of the microorganism, which is a separate reportable procedure. Once this initial identification is established, additional cultures may be conducted to refine the identification further. The identification process utilizes either a direct or an amplified probe technique. In the case of the direct probe technique, as described in CPT® Code 87149, lysate is employed to rupture the cells and release their nucleic acids, which are then tested for the presence of specific organisms. The amplified probe technique, as indicated by CPT® Code 87150, employs methods such as polymerase chain reaction (PCR) to create multiple copies of the nucleic acids, which is particularly useful when the microorganism is present in low quantities that may not be detectable by direct probing methods. This comprehensive approach ensures accurate identification of the organism, facilitating appropriate clinical decisions and treatment options.