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Official Description

Cytopathology, smears, any other source; screening and interpretation

© Copyright 2026 American Medical Association. All rights reserved.

Common Language Description

CPT® Code 88160 refers to a specific laboratory test known as cytopathology, which involves the examination of smears obtained from various sources. This procedure is essential for diagnosing a range of conditions, including malignant and premalignant diseases, infections, autoimmune disorders, inflammation, immune reactions, cell aging, and amyloidosis. Cytopathology focuses on the microscopic analysis of cells that either naturally shed from tissues or can be collected from body surfaces through methods such as washing or brushing. The process begins with the collection of samples, which must be reported separately. Once the samples are obtained, a technician or pathologist prepares the slides for examination. The pathologist then meticulously analyzes the slides under a microscope, assessing the cellular characteristics and abnormalities present. Following this examination, a comprehensive written report detailing the findings is generated. It is important to note that CPT® Code 88160 specifically pertains to the screening and interpretation of these cytopathological samples, distinguishing it from other related codes that may involve additional preparation or extended studies of the samples.

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