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Optical endomicroscopy is a specialized imaging technique that allows for the in vivo visualization and detailed characterization of mucosal tissue and the pathophysiological processes occurring at the microscopic level. This procedure utilizes advanced laser light magnification to capture high-resolution images of cellular structures within the tissue. During an endoscopic procedure, optical endomicroscopic images are obtained, which can be analyzed either in real time or at a later date. The captured images are then submitted for histological evaluation, where each optical slice is meticulously reviewed for any histological changes. These changes are documented in a comprehensive written report, which provides critical insights into the tissue's condition. The CPT® Code 88375 is specifically designated for reporting the interpretation and report of these optical endomicroscopic images, and it is important to note that this code is reported only once per endoscopic session, regardless of the number of optical slices that are submitted for evaluation.
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