CPT® Code 90657

The CPT® Code 90657 refers to a specific formulation of the influenza virus vaccine, known as the trivalent inactivated influenza vaccine (IIV3). This vaccine is designed for intramuscular administration and is characterized by its split virus composition. Unlike immune globulins, which offer short-term, passive immunity, vaccines like this one provide active, long-term immunity. This is achieved by introducing altered versions of the influenza virus into the recipient's immune system, prompting the body to produce its own antibodies. These antibodies enable the immune system to recognize and combat the actual virus upon future exposure. The trivalent influenza vaccine is formulated to include three distinct strains of the influenza virus: two strains from influenza type A and one strain from influenza type B. The production process involves using embryonated chicken eggs, where the virus is cultivated, harvested, and then inactivated using formaldehyde. Following this, the virus is concentrated, purified, and chemically disrupted to create a split virus, which is further purified to ensure safety and efficacy. It is important to note that the CPT® Code 90657 specifically pertains to a 0.25 mL dosage of this vaccine, while a different code, 90658, is used for a 0.5 mL dosage. These codes are strictly for reporting the vaccine product itself, and any intramuscular injection associated with the administration of the vaccine should be reported separately.