© Copyright 2026 American Medical Association. All rights reserved.
The CPT® Code 90682 refers to the quadrivalent influenza virus vaccine, specifically the recombinant influenza vaccine (RIV4). This vaccine is unique as it is produced without the use of the live influenza virus or eggs, making it suitable for individuals with egg allergies. The production process utilizes an insect virus known as baculovirus, combined with recombinant DNA technology, to generate the hemagglutinin (HA) protein, which is a key component of the influenza virus. This innovative method allows for a more rapid response in vaccine production, particularly beneficial during pandemic situations when swift immunization is critical. The quadrivalent formulation of this vaccine includes four full-strength recombinant HA proteins, providing protection against two strains of Influenza A and two strains of Influenza B. The vaccine is administered via intramuscular injection, and it is important to note that the administration of this vaccine is reported separately in medical billing and coding practices.
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