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Official Description

Influenza virus vaccine, quadrivalent (IIV4), split virus, 0.5 mL dosage, for intramuscular use

© Copyright 2026 American Medical Association. All rights reserved.

Common Language Description

The CPT® Code 90688 refers to a specific type of influenza virus vaccine known as the quadrivalent influenza vaccine (IIV4). This vaccine is designed to provide protection against four different strains of the influenza virus, specifically two strains of influenza type A and two strains of influenza type B. The term "quadrivalent" indicates that the vaccine targets multiple strains, enhancing its effectiveness in preventing influenza infections during the flu season. The vaccine is classified as a split virus vaccine, meaning that the virus particles have been chemically disrupted to create a form that is less likely to cause disease while still being able to stimulate an immune response. The dosage for this vaccine is 0.5 mL, and it is administered via intramuscular injection, which is a common method for delivering vaccines directly into the muscle tissue. This method allows for a more effective immune response compared to other routes of administration. It is important to note that the vaccine is produced using embryonated chicken eggs, where the virus is cultivated, harvested, and then inactivated with formaldehyde to ensure safety. The vaccine's formulation is crucial for inducing long-term immunity, as it prompts the immune system to recognize and remember the influenza virus, enabling the body to produce antibodies upon subsequent exposures. For billing purposes, it is essential to report the vaccine product separately from the administration of the intramuscular injection, with code 90688 specifically indicating the 0.5 mL dosage of the quadrivalent influenza vaccine.

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