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Code deleted. To report testing other than autonomic nervous system function testing, use 95999

Official Description

Simultaneous, independent, quantitative measures of both parasympathetic function and sympathetic function, based on time-frequency analysis of heart rate variability concurrent with time-frequency analysis of continuous respiratory activity, with mean heart rate and blood pressure measures, during rest, paced (deep) breathing, Valsalva maneuvers, and head-up postural change

© Copyright 2026 American Medical Association. All rights reserved.

Common Language Description

The CPT® Code 95943 refers to a specialized diagnostic procedure that evaluates the autonomic nervous system (ANS), which is comprised of two main components: the sympathetic and parasympathetic nervous systems. The sympathetic nervous system is primarily responsible for regulating blood pressure, while the parasympathetic nervous system plays a crucial role in controlling heart rate. This procedure involves the simultaneous and independent quantitative measurement of both branches of the ANS through a sophisticated analysis of heart rate variability (HRV) in conjunction with continuous respiratory activity. The assessment is conducted during various states, including rest, paced (deep) breathing, Valsalva maneuvers, and changes in posture, such as head-up positioning. By utilizing time-frequency analysis, this non-invasive technique provides valuable insights into the functioning of the autonomic nervous system. The test is typically performed with automated equipment, ensuring accuracy and reliability in the measurements obtained. This comprehensive evaluation aids healthcare professionals in understanding the balance and responsiveness of the autonomic nervous system, which is essential for maintaining homeostasis in the body.

© Copyright 2026 Coding Ahead. All rights reserved.

1. Indications

The procedure associated with CPT® Code 95943 is indicated for various clinical scenarios where assessment of autonomic nervous system function is necessary. The following conditions may warrant this evaluation:

  • Autonomic Dysfunction Assessment of patients exhibiting symptoms of autonomic dysfunction, which may include orthostatic hypotension, syncope, or unexplained fluctuations in heart rate and blood pressure.
  • Cardiovascular Disorders Evaluation of patients with cardiovascular conditions that may be influenced by autonomic regulation, such as heart failure or arrhythmias.
  • Diabetes Mellitus Monitoring of autonomic function in diabetic patients, particularly those with neuropathy, as diabetes can adversely affect autonomic regulation.
  • Postural Orthostatic Tachycardia Syndrome (POTS) Diagnosis and management of POTS, a condition characterized by an abnormal increase in heart rate upon standing.
  • Chronic Fatigue Syndrome Investigation of autonomic function in patients presenting with chronic fatigue syndrome, where autonomic dysregulation may be a contributing factor.

2. Procedure

The procedure for CPT® Code 95943 involves several key steps to ensure accurate measurement of autonomic function. Each step is critical for obtaining reliable data regarding heart rate variability and respiratory activity.

  • Step 1: Patient Preparation The patient is prepared for the test by ensuring they are in a comfortable environment, free from distractions. They may be instructed to avoid caffeine, nicotine, and certain medications prior to the test to prevent interference with autonomic function measurements.
  • Step 2: Baseline Measurements Initial baseline measurements of heart rate and blood pressure are taken while the patient is at rest. This establishes a reference point for subsequent evaluations during the procedure.
  • Step 3: Deep Breathing Phase The patient is guided through a series of paced deep breathing exercises. During this phase, heart rate variability is measured concurrently with respiratory activity to assess the parasympathetic response.
  • Step 4: Valsalva Maneuver The patient performs a Valsalva maneuver, which involves forceful exhalation against a closed airway. This maneuver is critical for evaluating the autonomic response and is monitored for changes in heart rate and blood pressure.
  • Step 5: Head-Up Postural Change The patient is then positioned upright to assess the autonomic response to postural changes. Heart rate and blood pressure are continuously monitored during this transition to evaluate sympathetic function.
  • Step 6: Data Analysis After completing the various phases, the collected data undergoes time-frequency analysis to provide quantitative measures of both sympathetic and parasympathetic function. This analysis is performed using automated equipment to ensure precision.

3. Post-Procedure

Post-procedure care for patients undergoing the evaluation associated with CPT® Code 95943 typically involves monitoring for any immediate adverse reactions, although the procedure is non-invasive and generally well-tolerated. Patients may be advised to resume normal activities unless otherwise directed by their healthcare provider. The results of the autonomic function tests are usually compiled and analyzed, with findings discussed in a follow-up appointment. This follow-up is essential for interpreting the results in the context of the patient's clinical presentation and determining any necessary further evaluations or interventions.

Short Descr PARASYMP&SYMP HRT RATE TEST
Medium Descr PARASYMP & SYMP NRV FUNCJ HRT RATE VARIABILITY
Long Descr Simultaneous, independent, quantitative measures of both parasympathetic function and sympathetic function, based on time-frequency analysis of heart rate variability concurrent with time-frequency analysis of continuous respiratory activity, with mean heart rate and blood pressure measures, during rest, paced (deep) breathing, Valsalva maneuvers, and head-up postural change
Status Code Carriers Price the Code
Global Days XXX - Global Concept Does Not Apply
PC/TC Indicator (26, TC) 1 - Diagnostic Tests for Radiology Services
Multiple Procedures (51) 0 - No payment adjustment rules for multiple procedures apply.
Bilateral Surgery (50) 0 - 150% payment adjustment for bilateral procedures does NOT apply.
Physician Supervisions 09 - Concept does not apply.
Assistant Surgeon (80, 82) 0 - Payment restriction for assistants at surgery applies to this procedure...
Co-Surgeons (62) 0 - Co-surgeons not permitted for this procedure.
Team Surgery (66) 0 - Team surgeons not permitted for this procedure.
Diagnostic Imaging Family 99 - Concept Does Not Apply
APC Status Indicator Procedure or Service, Not Discounted when Multiple
Type of Service (TOS) 1 - Medical Care
Berenson-Eggers TOS (BETOS) T2D - Other tests - other
MUE Not applicable/unspecified.
CCS Clinical Classification 7 - Other diagnostic nervous system procedures
GY Item or service statutorily excluded, does not meet the definition of any medicare benefit or, for non-medicare insurers, is not a contract benefit
Date
Action
Notes
2021-12-31 Deleted Code deleted. To report testing other than autonomic nervous system function testing, use 95999
2013-01-01 Added Added
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