CPT® Code 38214

The procedure described by CPT® Code 38214 pertains to the preparation of hematopoietic progenitor cells, which are essential components in the field of transplantation medicine. Hematopoietic progenitor cells are stem cells that have the potential to develop into various types of blood cells, including red blood cells, white blood cells, and platelets. These cells are typically harvested from a donor or patient and are preserved using a cryoprotectant solution to prevent damage during storage at low temperatures. The process of plasma depletion involves the reduction of the volume of these harvested cells by removing plasma, which is the liquid component of blood that carries cells and proteins. This step is crucial for ensuring that the cells are concentrated and ready for infusion into the recipient, thereby enhancing the effectiveness of the transplantation procedure. It is important to note that this code specifically applies when the volume reduction is achieved through plasma removal, distinguishing it from other methods of cell concentration, such as the removal of mononuclear cells or the buffy coat layer, which is covered under a different code (CPT® Code 38215).