CPT® Code 38215

The CPT® Code 38215 refers to the process of transplant preparation of hematopoietic progenitor cells, specifically focusing on the concentration of these cells within the plasma, mononuclear, or buffy coat layer. Hematopoietic progenitor cells are essential components in the field of transplantation, as they are responsible for the formation of blood cells. This procedure involves the treatment of previously harvested hematopoietic progenitor cells, which are typically collected for the purpose of transplantation. The harvested cells are preserved using a cryoprotectant solution, which helps to protect them during storage at low temperatures. When the time comes for infusion, these cells are thawed and prepared for administration to the patient. It is important to note that if the volume of cells is reduced by the removal of plasma from the harvested collection, the appropriate code to use would be 38214. Conversely, if the reduction in volume is achieved by extracting a portion of the concentration of mononuclear cells or the buffy coat layer of white blood cells from the plasma, then CPT® Code 38215 should be utilized. This distinction is crucial for accurate coding and billing in the context of hematopoietic cell transplantation.