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Official Description

Biopsy of pancreas, percutaneous needle

© Copyright 2026 American Medical Association. All rights reserved.

Common Language Description

The CPT® Code 48102 refers to a percutaneous needle biopsy of the pancreas, a minimally invasive procedure used to obtain tissue samples from the pancreas for diagnostic purposes. This procedure is typically indicated when there is a need to investigate pancreatic lesions, which may be indicative of various conditions, including tumors or other abnormalities. During the biopsy, the skin over the pancreas is prepared, and a local anesthetic is administered to minimize discomfort. A small incision is made to allow access to the pancreatic lesion. Utilizing imaging guidance techniques such as fluoroscopy, ultrasound, CT, or MRI, a thin-walled needle is carefully advanced through the incision and positioned next to the lesion. A second needle is then inserted into the lesion itself to collect tissue samples. This process may involve multiple passes to ensure that an adequate specimen is obtained for cytopathological examination, which is crucial for accurate diagnosis and subsequent treatment planning.

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