CPT® Code 48160

The CPT® Code 48160 refers to a surgical procedure known as a pancreatectomy, which involves the removal of all or part of the pancreas, followed by the autologous transplantation of either the pancreas itself or pancreatic islet cells. This procedure is typically indicated for patients with severe pancreatic conditions that necessitate the removal of pancreatic tissue. The term 'autologous' indicates that the transplanted tissue is sourced from the same patient, minimizing the risk of rejection. The surgery is performed through a subcostal or midline incision in the abdomen, allowing access to the pancreas. During the procedure, the gastrocolic omentum is divided to enter the lesser sac, and the splenic and hepatic flexures are mobilized to facilitate the removal of the pancreas. The pancreas is carefully dissected from surrounding structures, and if islet cell transplantation is performed, a collagenase solution is injected into the pancreas to isolate the islet cells from the acinar tissue. These cells can then be transplanted into the portal vein of the liver or beneath the kidneys, depending on the surgical plan. This complex procedure aims to address significant pancreatic dysfunction while attempting to preserve some pancreatic function through transplantation.