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Official Description

Hemoglobin; sulfhemoglobin, qualitative

© Copyright 2026 American Medical Association. All rights reserved.

Common Language Description

Sulfhemoglobinemia is a rare hematological condition characterized by the incorporation of sulfur atoms into the hemoglobin molecule, which impairs the red blood cells' ability to effectively bind and transport oxygen throughout the body. This condition is typically associated with an overdose of medications that contain sulfonamides or with occupational exposure to sulfur compounds. The presence of sulfhemoglobin in the blood can lead to significant health issues due to the reduced oxygen-carrying capacity of the affected red blood cells. To diagnose this condition, a blood sample is collected through a procedure known as venipuncture, which is separately reportable. The CPT® Code 83055 specifically refers to a qualitative blood test that is conducted to ascertain whether sulfhemoglobin is present in the sample. This test is distinct from CPT® Code 83060, which involves a quantitative assessment of sulfhemoglobin levels in whole blood using spectrophotometry. The qualitative test serves as an initial screening tool to identify the presence of sulfhemoglobin, guiding further diagnostic and therapeutic decisions.

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