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Official Description

Antibody; Treponema pallidum, confirmatory test (eg, FTA-abs)

© Copyright 2026 American Medical Association. All rights reserved.

Common Language Description

The CPT® Code 86781 refers to a confirmatory test for antibodies against Treponema pallidum, the bacterium responsible for syphilis. This test is crucial in diagnosing syphilis, as it helps confirm the presence of antibodies that indicate a current or past infection. The procedure involves collecting a blood sample from the patient, which is then analyzed in a laboratory setting. The confirmatory test, such as the Fluorescent Treponemal Antibody Absorption (FTA-abs) test, is typically performed after an initial screening test has indicated a potential syphilis infection. This step is essential for ensuring accurate diagnosis and appropriate treatment, as syphilis can lead to serious health complications if left untreated. The test specifically detects antibodies that the immune system produces in response to the Treponema pallidum bacterium, providing a reliable means of confirming the diagnosis of syphilis.

© Copyright 2026 Coding Ahead. All rights reserved.

1. Indications

The antibody test for Treponema pallidum, coded as CPT® 86781, is indicated for the following conditions:

  • Syphilis Diagnosis This test is performed to confirm the presence of antibodies in individuals who have tested positive on initial screening tests for syphilis.
  • Monitoring Treatment It may also be used to monitor the effectiveness of treatment in patients diagnosed with syphilis.
  • Assessment of Past Infection The test can help determine if a patient has had a past infection with Treponema pallidum, even if they are currently asymptomatic.

2. Procedure

The procedure for conducting the antibody test for Treponema pallidum involves several key steps:

  • Step 1: Patient Preparation The patient may be instructed to avoid certain medications or activities prior to the blood draw, although specific preparation guidelines can vary based on the laboratory's protocols.
  • Step 2: Blood Sample Collection A healthcare professional will collect a blood sample, typically from a vein in the arm, using a sterile needle and collection tube. This process is performed under aseptic conditions to minimize the risk of infection.
  • Step 3: Laboratory Analysis The collected blood sample is sent to a laboratory where it undergoes testing for the presence of antibodies against Treponema pallidum. The confirmatory test, such as the FTA-abs, is utilized to ensure accurate results.
  • Step 4: Result Interpretation Once the laboratory analysis is complete, the results are interpreted by a qualified healthcare professional. A positive result indicates the presence of antibodies, confirming a syphilis infection, while a negative result suggests the absence of the infection.

3. Post-Procedure

After the procedure, patients may experience minor discomfort at the site of the blood draw, such as bruising or soreness. These symptoms typically resolve quickly. It is important for patients to follow up with their healthcare provider to discuss the test results and any necessary next steps, including potential treatment options if the test is positive. Additionally, patients should be informed about the importance of notifying sexual partners if they are diagnosed with syphilis, as this is a sexually transmitted infection that requires prompt treatment to prevent further transmission.

Short Descr TREPONEMA PALLIDUM, CONFIRM
Medium Descr TREPONEMA PALLIDUM, CONFIRM
Long Descr ANTB TREPONEMA PALLIDUM CONFIRMATORY TST
APC Status Indicator Service Paid under Fee Schedule or Payment System other than OPPS
Type of Service (TOS) 5 - Diagnostic Laboratory
Berenson-Eggers TOS (BETOS) none
MUE Not applicable/unspecified.
CCS Clinical Classification 235 - Other Laboratory
Date
Action
Notes
2010-01-01 Deleted -
2004-01-01 Changed Code description changed.
1993-01-01 Added Code added.
Code
Description
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