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Code deleted, see 88348

Official Description

Electron microscopy; scanning

© Copyright 2026 American Medical Association. All rights reserved.

Common Language Description

The procedure described by CPT® Code 88349 involves the use of an electron microscope, specifically a scanning electron microscope, to identify tumors. Electron microscopy is a powerful imaging technique that utilizes a beam of electrons to create highly detailed images of specimens at a much higher resolution than traditional light microscopy. This advanced imaging capability allows for the visualization of cellular structures and components that are not discernible with standard optical methods. The scanning electron microscope (SEM) provides three-dimensional images of the specimen surface, which is particularly useful in the field of pathology for the examination of tumor samples. By employing this technology, pathologists can gain critical insights into the morphology and characteristics of tumors, aiding in accurate diagnosis and treatment planning. The use of CPT® Code 88349 is specifically designated for instances where a scanning electron microscope is utilized in the diagnostic process.

© Copyright 2026 Coding Ahead. All rights reserved.

1. Indications

The use of CPT® Code 88349 is indicated in specific scenarios where detailed examination of tumor samples is necessary. The following conditions warrant the application of this procedure:

  • Identification of Tumors This procedure is performed to accurately identify the presence of tumors in tissue samples, providing critical information for diagnosis.

2. Procedure

The procedure associated with CPT® Code 88349 involves several key steps that ensure the effective use of the scanning electron microscope for tumor identification. Each step is crucial for obtaining accurate and reliable results.

  • Preparation of the Specimen The first step involves preparing the tissue sample for examination. This may include fixation, dehydration, and embedding in a suitable medium to preserve the cellular structure and prevent degradation.
  • Mounting the Specimen Once prepared, the specimen is mounted onto a suitable holder that is compatible with the scanning electron microscope. This step is essential to ensure that the sample is stable and properly positioned for imaging.
  • Setting Up the Electron Microscope The scanning electron microscope is then calibrated and set up according to the specific requirements of the specimen being examined. This includes adjusting the electron beam and optimizing the imaging parameters to achieve the best possible resolution.
  • Imaging the Specimen The actual imaging process involves scanning the specimen with the electron beam. The interactions between the electrons and the sample generate signals that are converted into high-resolution images, allowing for detailed observation of the tumor's morphology.
  • Analysis of Images After imaging, the resulting images are analyzed by a qualified pathologist. This analysis is critical for identifying tumor characteristics, which can inform diagnosis and treatment decisions.

3. Post-Procedure

Post-procedure care following the use of CPT® Code 88349 typically involves the careful handling and storage of the specimen and the generated images. The pathologist may document findings and prepare a report based on the analysis of the images obtained from the scanning electron microscope. Additionally, any necessary follow-up actions, such as further testing or consultations, may be determined based on the results of the examination. It is important to ensure that all documentation is complete and accurate to support any subsequent clinical decisions.

Short Descr SCANNING ELECTRON MICROSCOPY
Medium Descr ELECTRON MICROSCOPY SCANNING
Long Descr Electron microscopy; scanning
Status Code Active Code
Global Days XXX - Global Concept Does Not Apply
PC/TC Indicator (26, TC) 1 - Diagnostic Tests for Radiology Services
Multiple Procedures (51) 0 - No payment adjustment rules for multiple procedures apply.
Bilateral Surgery (50) 0 - 150% payment adjustment for bilateral procedures does NOT apply.
Physician Supervisions 9 - Concept does not apply.
Assistant Surgeon (80, 82) 0 - Payment restriction for assistants at surgery applies to this procedure...
Co-Surgeons (62) 0 - Co-surgeons not permitted for this procedure.
Team Surgery (66) 0 - Team surgeons not permitted for this procedure.
Diagnostic Imaging Family 99 - Concept Does Not Apply
APC Status Indicator Ancillary Services
Type of Service (TOS) 5 - Diagnostic Laboratory
Berenson-Eggers TOS (BETOS) T1G - Lab tests - other (Medicare fee schedule)
MUE Not applicable/unspecified.
CCS Clinical Classification 234 - Pathology
Date
Action
Notes
2015-01-01 Deleted Code deleted, see 88348
Pre-1990 Added Code added.
Code
Description
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