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Official Description

Determinative histochemistry to identify chemical components (eg, copper, zinc)

© Copyright 2026 American Medical Association. All rights reserved.

Common Language Description

The CPT® Code 88318 refers to a specific laboratory procedure known as determinative histochemistry. This procedure involves the examination of cells within a tissue sample to identify their chemical components, such as copper and zinc. During this process, a pathologist or laboratory technician utilizes advanced microscopy techniques to analyze the tissue at a cellular level. The goal is to detect and characterize the presence of specific chemicals that may be indicative of various physiological or pathological conditions. By identifying these chemical components, healthcare professionals can gain valuable insights into the underlying biological processes occurring within the tissue, which can aid in diagnosis and treatment planning. This procedure is particularly useful in research and clinical settings where understanding the chemical makeup of cells is crucial for evaluating disease states or the effects of treatments.

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