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The CPT® Code 88347 refers to an immunofluorescent study that employs an indirect method for testing antibodies. In this procedure, antibodies are treated with a fluorescent dye, which allows for the visualization of specific antigens in suspected diseased red blood cells. This technique is particularly useful in diagnosing various conditions related to blood disorders and autoimmune diseases. The test is performed by applying the fluorescently labeled antibodies to a sample, which can be blood serum rather than a tissue sample, to identify the presence of specific antigens. It is important to note that this code is billed once for each antibody utilized in the testing process, ensuring that the complexity and scope of the diagnostic work are accurately represented in the coding. The use of the indirect method indicates that the antibodies are not directly bound to the target antigens but rather require a secondary antibody for detection, enhancing the sensitivity and specificity of the test results.
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