CPT® Code 90622

The CPT® Code 90622 refers to the Vaccinia (smallpox) virus vaccine, which is a live, lyophilized preparation intended for percutaneous use. This vaccine is designed to provide active, long-term immunity by introducing a modified version of the smallpox virus into the recipient's immune system. The immune system responds by producing antibodies that specifically target the virus, enabling the body to recognize and combat the virus if exposed in the future. Smallpox, caused by the variola virus, is a severe and potentially fatal disease that has been eradicated through vaccination efforts. However, the risk of exposure to different strains of vaccinia remains, particularly for healthcare and laboratory workers who may handle the vaccine or come into contact with infected individuals. The lyophilized form of the vaccine is created through a freeze-drying process that removes moisture from the live virus under controlled vacuum conditions, allowing for safe storage and transport. Prior to administration, the powder must be reconstituted to achieve the correct dosage of 0.3 mL. It is important to note that this code specifically pertains to the vaccine product itself and does not encompass the procedure of administering the vaccine via percutaneous methods.