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Official Description

Yellow fever vaccine, live, for subcutaneous use

© Copyright 2026 American Medical Association. All rights reserved.

Common Language Description

The CPT® Code 90717 refers to the yellow fever vaccine, which is a live vaccine administered via subcutaneous injection. Vaccines, such as this one, are designed to provide active, long-term immunity by stimulating the recipient's immune system. Unlike immune globulins that offer short-term, passive immunity, vaccines expose the immune system to altered forms of specific viruses or bacteria. This exposure prompts the immune system to produce its own antibodies, which are crucial for fighting off infections. Once vaccinated, the body retains a memory of how to produce these antibodies, allowing for a quicker and more effective response upon subsequent exposure to the actual pathogen. The yellow fever vaccine specifically contains a live, attenuated virus, meaning the virus has been weakened to the point where it can still provoke an immune response without causing the disease itself. This vaccine is particularly important for individuals traveling to areas where yellow fever is endemic, such as parts of South America and sub-Saharan Africa, as it helps protect against this potentially severe viral infection.

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