CPT® Code 90758

The CPT® Code 90758 refers to the Zaire ebolavirus vaccine, which is a live vaccine administered via intramuscular injection. Vaccines, unlike immune globulins that offer short-term, passive immunity, provide active and long-term immunity. This is achieved by exposing the recipient's immune system to altered forms of specific viruses or bacteria, prompting the immune system to produce its own antibodies against the microorganism. The immune system retains a memory of how to produce these antibodies, allowing for a quicker and more effective response upon subsequent exposures to the same antigen. The Zaire ebolavirus vaccine specifically contains an attenuated, or weakened, form of the live virus, which is designed to stimulate an immune response without causing the actual disease. This vaccine is crucial for protecting against the rare but serious Ebola virus disease (EBV), primarily used as a pre-exposure prophylactic measure for individuals aged 18 and older who are at occupational risk of exposure. This includes laboratory personnel and healthcare workers operating in designated facilities. The Ebola virus is known to exist in certain animal populations across various sub-Saharan African countries and can be transmitted to humans through contact with infected animals, subsequently spreading from person to person.