© Copyright 2026 American Medical Association. All rights reserved.
The CPT® Code 90738 refers to the Japanese encephalitis virus vaccine, which is an inactivated vaccine intended for intramuscular use. This vaccine is designed to provide long-term immunity against the Japanese encephalitis (JE) virus, a pathogen that can cause serious inflammation of the brain. Unlike immune globulins that offer only temporary, passive immunity, vaccines like this one stimulate the recipient's immune system to recognize and combat the virus by producing its own antibodies. When administered, the vaccine introduces an altered version of the JE virus, prompting the immune system to learn how to respond effectively to future exposures. The JE virus is primarily transmitted through the bites of infected mosquitoes and is prevalent in certain rural areas of Asia, making vaccination crucial for individuals living in or traveling to these regions. It is important to note that this code specifically reports the supply of the vaccine itself and does not include the administration of the intramuscular injection, which is a separate consideration in the billing process.
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