© Copyright 2026 American Medical Association. All rights reserved.
The CPT® Code 49021 refers to the procedure for the drainage of a peritoneal abscess or localized peritonitis, specifically excluding appendiceal abscesses. A peritoneal abscess is defined as a localized collection of pus that occurs within the peritoneum, which is the membrane lining the abdominal cavity. This condition may also be referred to as an intraperitoneal abscess. Localized peritonitis, on the other hand, is characterized by inflammation of the peritoneal tissue in a specific, circumscribed area. The procedure can be performed using either an open technique, as described in CPT® Code 49020, or a percutaneous technique, as indicated by CPT® Code 49021. In the percutaneous approach, a needle is inserted into the suspected abscess cavity to aspirate fluid, which helps confirm the presence of pus. Following this, a drainage catheter is placed into the abscess cavity, often with the assistance of imaging guidance such as fluoroscopy, ultrasound, or CT. The abscess is then drained, and the cavity is thoroughly flushed with sterile saline or an antibiotic solution to ensure the removal of all debris, including pus, blood, and necrotic tissue. The catheter remains in place to facilitate continuous drainage of the abscess cavity, promoting healing and preventing further complications.
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