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Official Description

Hemoglobin; sulfhemoglobin, quantitative

© Copyright 2026 American Medical Association. All rights reserved.

Common Language Description

Sulfhemoglobinemia is a rare hematological condition characterized by the incorporation of sulfur atoms into the hemoglobin molecule, which impairs the red blood cells' ability to effectively bind and transport oxygen throughout the body. This condition is typically associated with an overdose of medications that contain sulfonamides or with occupational exposure to sulfur compounds. The diagnosis of sulfhemoglobinemia involves the quantitative measurement of sulfhemoglobin levels in whole blood, which is performed using a technique known as spectrophotometry. This specific test, identified by CPT® Code 83060, is crucial for assessing the severity of the condition and guiding appropriate clinical management. It is important to note that a blood sample for this test is obtained through a separately reportable venipuncture, ensuring that the procedure is accurately documented and billed. In contrast to CPT® Code 83055, which is used for a qualitative assessment to determine the presence of sulfhemoglobin, CPT® Code 83060 provides a quantitative analysis, offering more detailed information regarding the concentration of sulfhemoglobin in the blood.

© Copyright 2026 Coding Ahead. All rights reserved.

1. Indications

The quantitative measurement of sulfhemoglobin levels is indicated in specific clinical scenarios where sulfhemoglobinemia is suspected. The following conditions may warrant this testing:

  • Medication Overdose An overdose of sulfonamide-containing medications can lead to sulfhemoglobinemia, necessitating testing to evaluate the extent of hemoglobin alteration.
  • Occupational Exposure Individuals who have been exposed to sulfur compounds in their work environment may develop sulfhemoglobinemia, prompting the need for quantitative assessment.
  • Symptoms of Hypoxia Patients presenting with symptoms indicative of reduced oxygen-carrying capacity, such as cyanosis, fatigue, or shortness of breath, may require this test to determine if sulfhemoglobinemia is a contributing factor.

2. Procedure

The procedure for measuring sulfhemoglobin levels involves several key steps, which are outlined as follows:

  • Step 1: Patient Preparation Prior to the blood draw, the patient should be informed about the procedure and any necessary preparations, such as fasting or avoiding certain medications, if applicable.
  • Step 2: Venipuncture A qualified healthcare professional performs a venipuncture to obtain a blood sample. This step is critical as it ensures that the sample is collected in a manner that minimizes contamination and preserves the integrity of the blood for accurate testing.
  • Step 3: Sample Handling The collected blood sample must be properly labeled and handled according to laboratory protocols to prevent degradation of the sample prior to analysis.
  • Step 4: Spectrophotometric Analysis The laboratory performs the quantitative analysis of sulfhemoglobin using spectrophotometry, a method that measures the absorbance of light by the blood sample at specific wavelengths to determine the concentration of sulfhemoglobin present.
  • Step 5: Result Interpretation Once the analysis is complete, the results are interpreted by a qualified healthcare professional, who will assess the sulfhemoglobin levels in the context of the patient's clinical presentation and history.

3. Post-Procedure

After the procedure, the patient may be monitored for any immediate adverse reactions to the venipuncture, such as bleeding or discomfort at the site. The healthcare provider will discuss the results of the sulfhemoglobin test with the patient, including any necessary follow-up actions or treatments based on the findings. It is essential to ensure that the patient understands the implications of the test results and any further evaluations or interventions that may be required to address the underlying cause of sulfhemoglobinemia.

Short Descr HGB SULFHEMOGLOBIN QUAN
Medium Descr HEMOGLOBIN SULFHEMOGLOBIN QUANTITATIVE
Long Descr Hemoglobin; sulfhemoglobin, quantitative
Status Code Statutory Exclusion (from MPFS, may be paid under other methodologies)
Global Days XXX - Global Concept Does Not Apply
PC/TC Indicator (26, TC) 9 - Not Applicable
Multiple Procedures (51) 9 - Concept does not apply.
Bilateral Surgery (50) 9 - Concept does not apply.
Physician Supervisions 09 - Concept does not apply.
Assistant Surgeon (80, 82) 9 - Concept does not apply.
Co-Surgeons (62) 9 - Concept does not apply.
Team Surgery (66) 9 - Concept does not apply.
Diagnostic Imaging Family 99 - Concept Does Not Apply
CLIA Waived (QW) No
APC Status Indicator Conditionally packaged laboratory tests
Type of Service (TOS) 5 - Diagnostic Laboratory
Berenson-Eggers TOS (BETOS) T1H - Lab tests - other (non-Medicare fee schedule)
MUE 1
CCS Clinical Classification 233 - Laboratory - Chemistry and Hematology
90 Reference (outside) laboratory: when laboratory procedures are performed by a party other than the treating or reporting physician or other qualified health care professional, the procedure may be identified by adding modifier 90 to the usual procedure number.
GA Waiver of liability statement issued as required by payer policy, individual case
Date
Action
Notes
2023-01-01 Note Short description changed.
Pre-1990 Added Code added.
Code
Description
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