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Official Description

Hemoglobin; thermolabile

© Copyright 2026 American Medical Association. All rights reserved.

Common Language Description

The CPT® Code 83065 refers to the laboratory test for measuring thermolabile hemoglobin. In this procedure, a blood sample is collected from the patient and then subjected to a controlled heating process. This heating effectively denatures the globin component of hemoglobin, allowing for further analysis and study of the hemoglobin structure and function. The term "thermolabile" indicates that the hemoglobin is sensitive to heat, which is a critical aspect of this test as it helps in identifying specific hemoglobin variants or abnormalities that may be present in the blood. This test is particularly useful in the diagnosis and management of various hematological conditions, providing essential information about the patient's hemoglobin profile.

© Copyright 2026 Coding Ahead. All rights reserved.

1. Indications

The procedure associated with CPT® Code 83065 is indicated for the evaluation of hemoglobin variants and abnormalities. It is particularly useful in the following scenarios:

  • Diagnosis of Hemoglobinopathies This test is performed to identify specific hemoglobin disorders, such as sickle cell disease or thalassemia, which can significantly impact a patient's health.
  • Monitoring of Hemoglobin Levels It is used to monitor changes in hemoglobin levels over time, especially in patients with known hemoglobin disorders.
  • Assessment of Anemia The test can help in the assessment of various types of anemia, providing insights into the underlying causes related to hemoglobin abnormalities.

2. Procedure

The procedure for CPT® Code 83065 involves several key steps that ensure accurate testing of thermolabile hemoglobin:

  • Step 1: Blood Sample Collection A qualified healthcare professional collects a blood sample from the patient, typically via venipuncture. The sample must be handled with care to prevent contamination and ensure the integrity of the hemoglobin for testing.
  • Step 2: Heating the Sample The collected blood sample is subjected to a controlled heating process. This step is crucial as it effectively denatures the globin portion of the hemoglobin, rendering it thermolabile. The specific temperature and duration of heating are critical to achieving accurate results.
  • Step 3: Analysis After the heating process, the sample is analyzed using appropriate laboratory techniques to assess the hemoglobin variants present. This analysis may involve various methods, including electrophoresis or chromatography, to separate and identify different hemoglobin types.

3. Post-Procedure

Post-procedure care for patients undergoing the hemoglobin thermolabile test is generally minimal, as it is a laboratory test rather than an invasive procedure. Patients may resume normal activities immediately after the blood draw. However, it is essential for healthcare providers to communicate the results of the test to the patient once they are available, as this information can be critical for diagnosis and treatment planning. Additionally, any necessary follow-up tests or evaluations should be discussed based on the findings from the hemoglobin analysis.

Short Descr HEMOGLOBIN THERMOLABILE
Medium Descr HEMOGLOBIN THERMOLABILE
Long Descr Hemoglobin; thermolabile
Status Code Statutory Exclusion (from MPFS, may be paid under other methodologies)
Global Days XXX - Global Concept Does Not Apply
PC/TC Indicator (26, TC) 9 - Not Applicable
Multiple Procedures (51) 9 - Concept does not apply.
Bilateral Surgery (50) 9 - Concept does not apply.
Physician Supervisions 09 - Concept does not apply.
Assistant Surgeon (80, 82) 9 - Concept does not apply.
Co-Surgeons (62) 9 - Concept does not apply.
Team Surgery (66) 9 - Concept does not apply.
Diagnostic Imaging Family 99 - Concept Does Not Apply
CLIA Waived (QW) No
APC Status Indicator Conditionally packaged laboratory tests
Type of Service (TOS) 5 - Diagnostic Laboratory
Berenson-Eggers TOS (BETOS) T1H - Lab tests - other (non-Medicare fee schedule)
MUE 1
CCS Clinical Classification 233 - Laboratory - Chemistry and Hematology
Date
Action
Notes
2023-01-01 Note Short description changed.
Pre-1990 Added Code added.
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